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- W2030858068 abstract "Mechanical manipulation of DNA by forced extension can lead double-stranded DNA (dsDNA) to structurally transform from a helical form to a linear zipper-like form. By employing classical molecular dynamics and quantum mechanical nonequilibrium Green's function-based transport simulations, we show the ability of graphene nanopores to discern different dsDNA conformations, in a helical to zipper transition, using transverse electronic conductance. In particular, conductance oscillations due to helical dsDNA vanish as dsDNA extends from a helical form to a zipper form while it is transported through the nanopore. The predicted ability to detect conformational changes in dsDNA via transverse electronic conductance can widen the potential use of graphene-based nanosensors for DNA detection." @default.
- W2030858068 created "2016-06-24" @default.
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- W2030858068 date "2014-10-17" @default.
- W2030858068 modified "2023-10-17" @default.
- W2030858068 title "Electronic detection of dsDNA transition from helical to zipper conformation using graphene nanopores" @default.
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- W2030858068 doi "https://doi.org/10.1088/0957-4484/25/44/445105" @default.
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