FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2030878499> ?p ?o ?g. }

• W2030878499 abstract "Local application of acetylcholine (ACh; 0.3 mM, 20 microl) elicited bi-phasic elevation of intracellular Ca2+ concentrations (contractile fast and non-contractile slow Ca2- signal measured as aequorin luminescence) in diaphragm muscle preparation. A neuronal nicotinic antagonist methyllycaconitine (MLA; 0.01-1 microM), which did not affect the fast Ca2+ transients and twitch tension, concentration-dependently depressed only the slow Ca2+ component. Ca2+ channel blockers, Cd2+ (200 microM), nitrendipine (1 microM), verapamil (1 microM) and diltiazem (1 microM), or a Na+ channel blocker tetrodotoxin (TTX; 0.1 microM) failed to prevent the generation of slow Ca2+ response. Perfusion of ACh (1 microM) to isolated single skeletal (flexor digitorum brevis) muscle cells pretreated with TTX (0.1 microM) also elicited a slow Ca2+ signal measured as confocal imaging with a fluorescent dye, fluo-3, at the endplate region. MLA (1 microM) antagonized against the ACh perfusion-elicited slow Ca2+ signal. Perfusion of choline (1 mM), a neuronal nicotinic agonist, also elicited the MLA-sensitive slow Ca2+ signal. These results strongly suggest that the ACh-induced slow Ca2+ signal reflects Ca2+ entry through a postsynaptic MLA-sensitive neuronal nicotinic ACh receptor subtype at the neuromuscular junction." @default.
• W2030878499 created "2016-06-24" @default.
• W2030878499 creator A5003849424 @default.
• W2030878499 creator A5055757122 @default.
• W2030878499 creator A5081735051 @default.
• W2030878499 date "1999-01-01" @default.
• W2030878499 modified "2023-09-27" @default.
• W2030878499 title "Methyllycaconitine-sensitive neuronal nicotinic receptor-operated slow Ca2+ signal by local application or perfusion of ACh at the mouse neuromuscular junction" @default.
• W2030878499 cites W1588765091 @default.
• W2030878499 cites W1629345179 @default.
• W2030878499 cites W1669322589 @default.
• W2030878499 cites W1900806927 @default.
• W2030878499 cites W1965438922 @default.
• W2030878499 cites W1978804738 @default.
• W2030878499 cites W1979753120 @default.
• W2030878499 cites W1982683622 @default.
• W2030878499 cites W1985231116 @default.
• W2030878499 cites W1988299334 @default.
• W2030878499 cites W1994146507 @default.
• W2030878499 cites W1994188838 @default.
• W2030878499 cites W1998470888 @default.
• W2030878499 cites W2005491437 @default.
• W2030878499 cites W2018147112 @default.
• W2030878499 cites W2022617420 @default.
• W2030878499 cites W2023103573 @default.
• W2030878499 cites W2036957884 @default.
• W2030878499 cites W2046075911 @default.
• W2030878499 cites W2052312234 @default.
• W2030878499 cites W2053214995 @default.
• W2030878499 cites W2057551724 @default.
• W2030878499 cites W2057949770 @default.
• W2030878499 cites W2058004863 @default.
• W2030878499 cites W2061675635 @default.
• W2030878499 cites W2069090908 @default.
• W2030878499 cites W2075324075 @default.
• W2030878499 cites W2075419607 @default.
• W2030878499 cites W2080410707 @default.
• W2030878499 cites W2081083184 @default.
• W2030878499 cites W2092727345 @default.
• W2030878499 cites W2095948686 @default.
• W2030878499 cites W2099542365 @default.
• W2030878499 cites W2131003845 @default.
• W2030878499 cites W2131310568 @default.
• W2030878499 cites W2429480698 @default.
• W2030878499 doi "https://doi.org/10.1016/s0168-0102(98)00109-6" @default.
• W2030878499 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10096467" @default.
• W2030878499 hasPublicationYear "1999" @default.
• W2030878499 type Work @default.
• W2030878499 sameAs 2030878499 @default.
• W2030878499 citedByCount "4" @default.
• W2030878499 countsByYear W20308784992013 @default.
• W2030878499 crossrefType "journal-article" @default.
• W2030878499 hasAuthorship W2030878499A5003849424 @default.
• W2030878499 hasAuthorship W2030878499A5055757122 @default.
• W2030878499 hasAuthorship W2030878499A5081735051 @default.
• W2030878499 hasConcept C113217602 @default.
• W2030878499 hasConcept C12554922 @default.
• W2030878499 hasConcept C126322002 @default.
• W2030878499 hasConcept C134018914 @default.
• W2030878499 hasConcept C169760540 @default.
• W2030878499 hasConcept C170493617 @default.
• W2030878499 hasConcept C185592680 @default.
• W2030878499 hasConcept C188987157 @default.
• W2030878499 hasConcept C2775910092 @default.
• W2030878499 hasConcept C2776741303 @default.
• W2030878499 hasConcept C2777240379 @default.
• W2030878499 hasConcept C2778938600 @default.
• W2030878499 hasConcept C2779570518 @default.
• W2030878499 hasConcept C2780374058 @default.
• W2030878499 hasConcept C2909754679 @default.
• W2030878499 hasConcept C55493867 @default.
• W2030878499 hasConcept C71924100 @default.
• W2030878499 hasConcept C86803240 @default.
• W2030878499 hasConceptScore W2030878499C113217602 @default.
• W2030878499 hasConceptScore W2030878499C12554922 @default.
• W2030878499 hasConceptScore W2030878499C126322002 @default.
• W2030878499 hasConceptScore W2030878499C134018914 @default.
• W2030878499 hasConceptScore W2030878499C169760540 @default.
• W2030878499 hasConceptScore W2030878499C170493617 @default.
• W2030878499 hasConceptScore W2030878499C185592680 @default.
• W2030878499 hasConceptScore W2030878499C188987157 @default.
• W2030878499 hasConceptScore W2030878499C2775910092 @default.
• W2030878499 hasConceptScore W2030878499C2776741303 @default.
• W2030878499 hasConceptScore W2030878499C2777240379 @default.
• W2030878499 hasConceptScore W2030878499C2778938600 @default.
• W2030878499 hasConceptScore W2030878499C2779570518 @default.
• W2030878499 hasConceptScore W2030878499C2780374058 @default.
• W2030878499 hasConceptScore W2030878499C2909754679 @default.
• W2030878499 hasConceptScore W2030878499C55493867 @default.
• W2030878499 hasConceptScore W2030878499C71924100 @default.
• W2030878499 hasConceptScore W2030878499C86803240 @default.
• W2030878499 hasLocation W20308784991 @default.
• W2030878499 hasLocation W20308784992 @default.
• W2030878499 hasOpenAccess W2030878499 @default.
• W2030878499 hasPrimaryLocation W20308784991 @default.
• W2030878499 hasRelatedWork W1974100135 @default.
• W2030878499 hasRelatedWork W1990470650 @default.
• W2030878499 hasRelatedWork W2026331058 @default.
• W2030878499 hasRelatedWork W2030878499 @default.
• W2030878499 hasRelatedWork W2041281912 @default.

• next