Matches in SemOpenAlex for { <https://semopenalex.org/work/W2030889968> ?p ?o ?g. }
- W2030889968 abstract "Chromatin insulators affect interactions between promoters and enhancers/silencers and function as barriers for the spreading of repressive chromatin. Drosophila insulator protein dCTCF marks active promoters and boundaries of many histone H3K27 trimethylation domains associated with repressed chromatin. In particular, dCTCF binds to such boundaries between the parasegment-specific regulatory domains of the Bithorax complex. Here we demonstrate that the evolutionarily conserved protein ENY2 is recruited to the zinc-finger domain of dCTCF and is required for the barrier activity of dCTCF-dependent insulators in transgenic lines. Inactivation of ENY2 by RNAi in BG3 cells leads to the spreading of H3K27 trimethylation and Pc protein at several dCTCF boundaries. The results suggest that evolutionarily conserved ENY2 is responsible for barrier activity mediated by the dCTCF protein." @default.
- W2030889968 created "2016-06-24" @default.
- W2030889968 creator A5014729529 @default.
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- W2030889968 date "2014-08-01" @default.
- W2030889968 modified "2023-10-18" @default.
- W2030889968 title "Highly conserved ENY2/Sus1 protein binds toDrosophilaCTCF and is required for barrier activity" @default.
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- W2030889968 cites W1893658886 @default.
- W2030889968 cites W1964184081 @default.
- W2030889968 cites W1973342161 @default.
- W2030889968 cites W1973726475 @default.
- W2030889968 cites W1982700926 @default.
- W2030889968 cites W1992224549 @default.
- W2030889968 cites W1994210157 @default.
- W2030889968 cites W1995576030 @default.
- W2030889968 cites W1997025224 @default.
- W2030889968 cites W1998729431 @default.
- W2030889968 cites W2003354368 @default.
- W2030889968 cites W2006354791 @default.
- W2030889968 cites W2006788765 @default.
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- W2030889968 cites W2009018280 @default.
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- W2030889968 cites W2019937806 @default.
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- W2030889968 cites W2021580607 @default.
- W2030889968 cites W2022025085 @default.
- W2030889968 cites W2027781138 @default.
- W2030889968 cites W2028140379 @default.
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- W2030889968 cites W2029284014 @default.
- W2030889968 cites W2032105273 @default.
- W2030889968 cites W2033141201 @default.
- W2030889968 cites W2033624290 @default.
- W2030889968 cites W2035297312 @default.
- W2030889968 cites W2035374814 @default.
- W2030889968 cites W2035705082 @default.
- W2030889968 cites W2035726665 @default.
- W2030889968 cites W2037589637 @default.
- W2030889968 cites W2038372168 @default.
- W2030889968 cites W2040329023 @default.
- W2030889968 cites W2043439431 @default.
- W2030889968 cites W2049839274 @default.
- W2030889968 cites W2050603850 @default.
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- W2030889968 cites W2053317015 @default.
- W2030889968 cites W2059449682 @default.
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- W2030889968 cites W2070533601 @default.
- W2030889968 cites W2073869073 @default.
- W2030889968 cites W2076200643 @default.
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- W2030889968 cites W2088016816 @default.
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- W2030889968 cites W2111243591 @default.
- W2030889968 cites W2120448616 @default.
- W2030889968 cites W2120619403 @default.
- W2030889968 cites W2129454543 @default.
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- W2030889968 cites W2133712572 @default.
- W2030889968 cites W2133818312 @default.
- W2030889968 cites W2135185213 @default.
- W2030889968 cites W2142751244 @default.
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- W2030889968 cites W2147372710 @default.
- W2030889968 cites W2147428279 @default.
- W2030889968 cites W2147880260 @default.
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- W2030889968 doi "https://doi.org/10.4161/epi.32086" @default.
- W2030889968 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4169018" @default.
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- W2030889968 hasPublicationYear "2014" @default.
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