Matches in SemOpenAlex for { <https://semopenalex.org/work/W2030943218> ?p ?o ?g. }
Showing items 1 to 79 of
79
with 100 items per page.
- W2030943218 endingPage "272" @default.
- W2030943218 startingPage "257" @default.
- W2030943218 abstract "Male Jcl:SD rats were fed vitamin D2 (ergocalciferol) at levels of 0 (control), 0.39, 0.63 and 1.00% or 0 (control), 0.0195, 0.0315 and 0.050% in the diet for 7 days. All rats of the 0.39-1.00% groups expired on days 2 and 3, while some rats of the 0.0195-0.050% groups died on days 3-6. LD50 (median lethal 7-day cumulative dose calculated from food intake) is 110.5 mg/kg (0.0354% dietarily). In expired and surviving treated rats, several organs (kidney, heart, etc.) were found to be mineralized; there were also renal tubular injuries and pulmonary bleeding. Centrilobular necrosis of liver was detected only in dead rats. Treatment also caused hypercalcemia but did not decrease blood coagulation factors. These results suggest that vitamin D does not have the effect of impeding blood coagulation but that it is extremely toxic, probably due to the hypercalcemia it causes." @default.
- W2030943218 created "2016-06-24" @default.
- W2030943218 creator A5090450331 @default.
- W2030943218 date "1993-09-01" @default.
- W2030943218 modified "2023-09-25" @default.
- W2030943218 title "A large dose of ergocalciferol does not cause deficient blood coagulation but is extremely toxic to rats" @default.
- W2030943218 cites W1014043979 @default.
- W2030943218 cites W113696804 @default.
- W2030943218 cites W1534222671 @default.
- W2030943218 cites W1535348506 @default.
- W2030943218 cites W162015939 @default.
- W2030943218 cites W1633689651 @default.
- W2030943218 cites W180968156 @default.
- W2030943218 cites W1957381779 @default.
- W2030943218 cites W1985250698 @default.
- W2030943218 cites W1988365988 @default.
- W2030943218 cites W2010429214 @default.
- W2030943218 cites W2013184380 @default.
- W2030943218 cites W2014131740 @default.
- W2030943218 cites W2071156500 @default.
- W2030943218 cites W2078494459 @default.
- W2030943218 cites W2094196016 @default.
- W2030943218 cites W2118309312 @default.
- W2030943218 cites W2129226556 @default.
- W2030943218 cites W2130920745 @default.
- W2030943218 cites W2192185352 @default.
- W2030943218 cites W2229353265 @default.
- W2030943218 cites W2333330110 @default.
- W2030943218 cites W2087912078 @default.
- W2030943218 doi "https://doi.org/10.1016/0378-4274(93)90031-r" @default.
- W2030943218 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8212066" @default.
- W2030943218 hasPublicationYear "1993" @default.
- W2030943218 type Work @default.
- W2030943218 sameAs 2030943218 @default.
- W2030943218 citedByCount "3" @default.
- W2030943218 crossrefType "journal-article" @default.
- W2030943218 hasAuthorship W2030943218A5090450331 @default.
- W2030943218 hasConcept C126322002 @default.
- W2030943218 hasConcept C134018914 @default.
- W2030943218 hasConcept C2776940978 @default.
- W2030943218 hasConcept C2777621572 @default.
- W2030943218 hasConcept C2778382381 @default.
- W2030943218 hasConcept C2780091579 @default.
- W2030943218 hasConcept C2780106736 @default.
- W2030943218 hasConcept C2780959883 @default.
- W2030943218 hasConcept C503630168 @default.
- W2030943218 hasConcept C71924100 @default.
- W2030943218 hasConceptScore W2030943218C126322002 @default.
- W2030943218 hasConceptScore W2030943218C134018914 @default.
- W2030943218 hasConceptScore W2030943218C2776940978 @default.
- W2030943218 hasConceptScore W2030943218C2777621572 @default.
- W2030943218 hasConceptScore W2030943218C2778382381 @default.
- W2030943218 hasConceptScore W2030943218C2780091579 @default.
- W2030943218 hasConceptScore W2030943218C2780106736 @default.
- W2030943218 hasConceptScore W2030943218C2780959883 @default.
- W2030943218 hasConceptScore W2030943218C503630168 @default.
- W2030943218 hasConceptScore W2030943218C71924100 @default.
- W2030943218 hasIssue "3" @default.
- W2030943218 hasLocation W20309432181 @default.
- W2030943218 hasLocation W20309432182 @default.
- W2030943218 hasOpenAccess W2030943218 @default.
- W2030943218 hasPrimaryLocation W20309432181 @default.
- W2030943218 hasRelatedWork W1971607352 @default.
- W2030943218 hasRelatedWork W2020959757 @default.
- W2030943218 hasRelatedWork W2031457972 @default.
- W2030943218 hasRelatedWork W2042033030 @default.
- W2030943218 hasRelatedWork W2044943066 @default.
- W2030943218 hasRelatedWork W2069436261 @default.
- W2030943218 hasRelatedWork W2082456910 @default.
- W2030943218 hasRelatedWork W211032082 @default.
- W2030943218 hasRelatedWork W2134553307 @default.
- W2030943218 hasRelatedWork W3217225730 @default.
- W2030943218 hasVolume "69" @default.
- W2030943218 isParatext "false" @default.
- W2030943218 isRetracted "false" @default.
- W2030943218 magId "2030943218" @default.
- W2030943218 workType "article" @default.