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• W2030958082 abstract "Using immunocytochemical methods at the electron microscope level, immunoreactivity for both melanin-concentrating hormone (MCH) and alpha-melanocyte-stimulating hormone (alpha-MSH) has been demonstrated in the carp neurohypophysis. A double-labelling technique, using colloidal gold probes of different sizes showed that immunoreactivity to both molecules coexists within the same neurosecretory granules in some neurones, while in other neurones the granules exhibit only MCH-like immunoreactivity. These observations suggest that the two immunoreactivities are attributable to separate molecules; if they are derived from the same precursor molecule, then this must be cleaved differently in the two sets of neurones. The absence of adrenocorticotropic hormone (ACTH)-like immunostaining in any neurosecretory granule might suggest the alpha-MSH-like molecule is not derived from the conventional pro-opiomelanocortin precursor." @default.
• W2030958082 created "2016-06-24" @default.
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• W2030958082 date "1987-10-01" @default.
• W2030958082 modified "2023-09-27" @default.
• W2030958082 title "Ultrastructural demonstration that melanin-concentrating hormone-like and α-melanocyte-stimulating hormone-like immunoreactive molecules coexist in the same neurosecretory granules" @default.
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• W2030958082 doi "https://doi.org/10.1016/0304-3940(87)90466-6" @default.
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