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• W2031032817 abstract "The incidence of multiple malignant neoplasms in the upper aerodigestive tract is high and ranges from 7% to 20%. We make a retrospective study to evaluate the incidence of multiple malignant neoplasms in head and neck squamous cell carcinomas, their main characteristics and survival. We studied 103 multiple malignant neoplasms from an oncological database of 1330 patients with head and neck squamous cell carcinomas. We use the SPSS v.15 for analysis of the results. The incidence of multiple malignant neoplasms in our series is 7.73%. Tumours of the hypopharynx are the primary tumours most often associated with multiple malignant neoplasms (21.34%), followed by tumours of the oropharynx (15.38%). Lung tumours are the multiple malignant neoplasms most often associated (29.03%). The 5-year global survival is 33% from diagnosis of the second primary tumour, 78.02% of which are metachronous with an average of 40 months between the diagnosis of the primary tumour and the presentation of the second tumour. Multiple malignant neoplasms are very frequent in the head and neck area which shows the importance of thorough regular check-ups of these patients as the presence of multiple malignant neoplasms considerably worsens the prognosis. La frecuencia de neoplasias malignas múltiples en el tracto aerodigestivo superior es elevada y varía de un 7 a un 20%. Valoramos la frecuencia de segundos tumores primarios en carcinomas escamosos de cabeza y cuello, y determinamos sus principales características y la supervivencia. Realizamos un estudio retrospectivo con 103 segundos tumores primarios de una base de datos de 1.330 pacientes con carcinomas epidermoides de cabeza y cuello. Empleamos el programa SPSS v.15 para el análisis de resultados. La frecuencia de segundos tumores primarios en nuestra serie es del 7,73%. Los tumores primarios que más frecuentemente asocian segundos tumores primarios son los de hipofaringe (21,34%), seguidos de los de orofaringe (15,38%). El segundo tumor primario más frecuentemente asociado es el de pulmón (29,03%). La supervivencia general es del 33% a los 5 años del diagnóstico del segundo tumor primario. El 78,02% de los segundos tumores primarios son metacrónicos, con una media de 40 meses entre el diagnóstico del tumor primario y la aparición del segundo tumor primario. Los segundos tumores primarios son muy frecuentes en el área de cabeza y cuello, lo cual resalta la importancia de un control periódico y exhaustivo de estos pacientes ya que su aparición conlleva un ensombrecimiento importante del pronóstico." @default.
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• W2031032817 date "2008-01-01" @default.
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• W2031032817 title "Malignant Multiple Neoplasms in Head and Neck Squamous Cell Carcinoma" @default.
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• W2031032817 doi "https://doi.org/10.1016/s2173-5735(08)70267-9" @default.
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