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- W2031034560 abstract "Synaptic plasticity in the motor cortex is involved at least in some forms of motor learning. Recent evidence showed that the extent of practice-dependent plasticity in the motor cortex can be purposefully enhanced by experimental manipulation. One way of improving motor learning is to transiently increase the excitability of the motor cortex during motor learning. This can be achieved by weakening the excitability of intracortical inhibitory circuits concurrently with practice. This principle is being referred to as gating. Another strategy to boost learning is to decrease the threshold for induction of synaptic plasticity by lowering neuronal activity in the motor cortex before practice. This approach invokes homeostatic metaplasticity. Here we highlight how transcranial brain stimulation can exploit gating and homeostatic metaplasticity to enhance motor learning in healthy subjects and in patients after stroke." @default.
- W2031034560 created "2016-06-24" @default.
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- W2031034560 date "2008-01-01" @default.
- W2031034560 modified "2023-10-09" @default.
- W2031034560 title "Modifying motor learning through gating and homeostatic metaplasticity" @default.
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- W2031034560 doi "https://doi.org/10.1016/j.brs.2007.08.003" @default.
- W2031034560 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20633369" @default.
- W2031034560 hasPublicationYear "2008" @default.
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