Matches in SemOpenAlex for { <https://semopenalex.org/work/W2031036605> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2031036605 endingPage "240" @default.
- W2031036605 startingPage "237" @default.
- W2031036605 abstract "Behcet's disease (BD) is a multi-system inflammatory disorder of poorly understood pathogenesis, which is characterized by oral aphtosis, genital ulcers and uveitis.To assess the role of CD3+CD4-CD8- double negative (DN) T cells in pathogenesis of Behcet's disease.Ten BD patients (age 12.2+/-2.2 years, 7 in remission, 3 in exacerbation state) treated at the Pediatric Rheumatology unit of Soroka University Medical Center and 3 age-matched controls participated in the study.Peripheral blood lymphocytes of study subjects were isolated and stained with fluorescein-labeled anti-CD45, CD3, CD4, CD8 antibodies and analyzed by FACS assay.Proportion of CD4-CD8- DN T cells was significantly increased in BD patients (n=10) as compared to healthy controls (6.2+/-3.4% vs. 3.2+/-1.1% of total CD3+ cells, p<0.05), this cell group was additionally enhanced in BD exacerbation, compared to patients in remission (10+/-4.1% vs. 4.7+/-1.2%, p<0.05, respectively). DN T cells were significantly increased in BD patients in remission, compared to healthy controls (4.7+1.2% vs. 3.2+1.1% of total CD3+ cells, p<0.05, respectively).Behcet's disease is characterized by increased proportion of CD3+CD4-CD8- double negative T cells in peripheral blood. Further studies, that include additional immunophenotyping and analysis of gene expression, aimed at characterization of these cells are currently underway." @default.
- W2031036605 created "2016-06-24" @default.
- W2031036605 creator A5032163842 @default.
- W2031036605 creator A5042376587 @default.
- W2031036605 creator A5086750804 @default.
- W2031036605 date "2007-03-01" @default.
- W2031036605 modified "2023-10-10" @default.
- W2031036605 title "Increased proportion of CD3+CD4−CD8− double-negative T cells in peripheral blood of children with Behcet's disease" @default.
- W2031036605 cites W1972439921 @default.
- W2031036605 cites W1985784674 @default.
- W2031036605 cites W1987069221 @default.
- W2031036605 cites W1988577661 @default.
- W2031036605 cites W1989029799 @default.
- W2031036605 cites W2015772244 @default.
- W2031036605 cites W2016950973 @default.
- W2031036605 cites W2019899379 @default.
- W2031036605 cites W2028404309 @default.
- W2031036605 cites W2049337385 @default.
- W2031036605 cites W2078163768 @default.
- W2031036605 cites W2079657717 @default.
- W2031036605 cites W2097385117 @default.
- W2031036605 cites W2097622491 @default.
- W2031036605 cites W2116361650 @default.
- W2031036605 cites W2121960829 @default.
- W2031036605 cites W2154527176 @default.
- W2031036605 doi "https://doi.org/10.1016/j.autrev.2006.08.008" @default.
- W2031036605 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17317615" @default.
- W2031036605 hasPublicationYear "2007" @default.
- W2031036605 type Work @default.
- W2031036605 sameAs 2031036605 @default.
- W2031036605 citedByCount "23" @default.
- W2031036605 countsByYear W20310366052012 @default.
- W2031036605 countsByYear W20310366052013 @default.
- W2031036605 countsByYear W20310366052014 @default.
- W2031036605 countsByYear W20310366052017 @default.
- W2031036605 countsByYear W20310366052018 @default.
- W2031036605 countsByYear W20310366052019 @default.
- W2031036605 countsByYear W20310366052020 @default.
- W2031036605 countsByYear W20310366052021 @default.
- W2031036605 countsByYear W20310366052022 @default.
- W2031036605 countsByYear W20310366052023 @default.
- W2031036605 crossrefType "journal-article" @default.
- W2031036605 hasAuthorship W2031036605A5032163842 @default.
- W2031036605 hasAuthorship W2031036605A5042376587 @default.
- W2031036605 hasAuthorship W2031036605A5086750804 @default.
- W2031036605 hasConcept C114684123 @default.
- W2031036605 hasConcept C126322002 @default.
- W2031036605 hasConcept C147483822 @default.
- W2031036605 hasConcept C167672396 @default.
- W2031036605 hasConcept C196166836 @default.
- W2031036605 hasConcept C198451711 @default.
- W2031036605 hasConcept C203014093 @default.
- W2031036605 hasConcept C2777014857 @default.
- W2031036605 hasConcept C2779134260 @default.
- W2031036605 hasConcept C2780942790 @default.
- W2031036605 hasConcept C2781428731 @default.
- W2031036605 hasConcept C71924100 @default.
- W2031036605 hasConcept C8891405 @default.
- W2031036605 hasConcept C90924648 @default.
- W2031036605 hasConcept C91394840 @default.
- W2031036605 hasConceptScore W2031036605C114684123 @default.
- W2031036605 hasConceptScore W2031036605C126322002 @default.
- W2031036605 hasConceptScore W2031036605C147483822 @default.
- W2031036605 hasConceptScore W2031036605C167672396 @default.
- W2031036605 hasConceptScore W2031036605C196166836 @default.
- W2031036605 hasConceptScore W2031036605C198451711 @default.
- W2031036605 hasConceptScore W2031036605C203014093 @default.
- W2031036605 hasConceptScore W2031036605C2777014857 @default.
- W2031036605 hasConceptScore W2031036605C2779134260 @default.
- W2031036605 hasConceptScore W2031036605C2780942790 @default.
- W2031036605 hasConceptScore W2031036605C2781428731 @default.
- W2031036605 hasConceptScore W2031036605C71924100 @default.
- W2031036605 hasConceptScore W2031036605C8891405 @default.
- W2031036605 hasConceptScore W2031036605C90924648 @default.
- W2031036605 hasConceptScore W2031036605C91394840 @default.
- W2031036605 hasIssue "4" @default.
- W2031036605 hasLocation W20310366051 @default.
- W2031036605 hasLocation W20310366052 @default.
- W2031036605 hasOpenAccess W2031036605 @default.
- W2031036605 hasPrimaryLocation W20310366051 @default.
- W2031036605 hasRelatedWork W205749915 @default.
- W2031036605 hasRelatedWork W2119678826 @default.
- W2031036605 hasRelatedWork W2135503300 @default.
- W2031036605 hasRelatedWork W2269535374 @default.
- W2031036605 hasRelatedWork W2326623647 @default.
- W2031036605 hasRelatedWork W2386350258 @default.
- W2031036605 hasRelatedWork W2409189456 @default.
- W2031036605 hasRelatedWork W3150532529 @default.
- W2031036605 hasRelatedWork W4313333869 @default.
- W2031036605 hasRelatedWork W4313347963 @default.
- W2031036605 hasVolume "6" @default.
- W2031036605 isParatext "false" @default.
- W2031036605 isRetracted "false" @default.
- W2031036605 magId "2031036605" @default.
- W2031036605 workType "article" @default.