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- W2031108889 abstract "Tal vez el caso de daño cerebral más famoso de la historia sea el sufrido por un trabajador del ferrocarril llamado Phineas Gage el 13 de septiembre de 1848; 12 años después, el 21 de mayo 1860, Gage muere tras una crisis comicial. En 1868 el Dr. Harlow publica el caso, describiendo por primera vez los cambios de personalidad experimentados por Gage tras la lesión. Uno pensaría que este artículo es el responsable de asegurar a Gage un lugar permanente en los anales de la neurología. Sin embargo no será así: pocas personas conocerán de la existencia de este artículo. No será hasta finales de la década de 1870 que Phineas Gage sea rescatado del olvido de la mano del Dr. David Ferrier, uno de los primeros defensores de la localización de la función cerebral. Para Ferrier Gage constituirá un trágico experimento natural que le permitirá corroborar que el córtex prefrontal no es un área no-funcional del cerebro. De tal forma, la lesión causada por una barra de hierro en el córtex prefrontal de Phineas Gage marcará los inicios de la investigación para comprender el enigma de esta fascinante región del cerebro. Perhaps the most famous brain injury in history was a penetrating wound suffered by a rail road worker named Phineas Gage on September 13, 1848. Twelve years after his injury, on the 21st of May, 1860 Phineas Gage died of an epileptic seizure. In 1868 Dr. Harlow gave an outline of Gage's case history and first disclosed his remarkable personality change. One might think this report would assure Gage a permanent place in the annals of neurology, but this was not the case. There was a good reason for this neglect: hardly anyone knew about Harlow's 1868 report. Dr. David Ferrier, an early proponent of the localisation of cerebral function, rescued Gage from obscurity and used the case as the highlight of his famous 1878 Goulstonian lectures. Gage had, through a tragic natural experiment, provided proof of what Ferrier's studies showed: the pre-frontal cortex was not a “non-functional” brain area. A rod going through the prefrontal cortex of Phineas Gage signalled the beginning of the quest to understand the enigmas of this fascinating region of the brain." @default.
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- W2031108889 title "Phineas Gage y el enigma del córtex prefrontal" @default.
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- W2031108889 doi "https://doi.org/10.1016/j.nrl.2010.07.015" @default.
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