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• W2031143568 abstract "MicroRNA (miRNA) processing in the cytoplasm produces a miRNA duplex containing the forward, miRNA strand and the reverse, miRNA* strand, which was thought to be degraded. However, recent evidence is challenging this dogma that miRNA* is simply a non-functional byproduct of miRNA biogenesis. We present a comprehensive review of evidence that miRNA* plays a significant role in cellular function and assembled a table outlining all of the publications before September 2011 that have reported on miRNA* activity in human disease. Furthermore, we will present unexpected diagnostic and therapeutic implications due to the active miRNA* status." @default.
• W2031143568 created "2016-06-24" @default.
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• W2031143568 date "2012-03-01" @default.
• W2031143568 modified "2023-10-13" @default.
• W2031143568 title "Functional relevance of miRNA* sequences in human disease" @default.
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• W2031143568 doi "https://doi.org/10.1016/j.mrfmmm.2011.10.014" @default.
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