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- W2031146519 startingPage "011012" @default.
- W2031146519 abstract "The letter-fluency task-induced response over the prefrontal cortex is investigated bilaterally on eight subjects using a recently developed compact, eight-channel, time-resolved, near-IR system. The cross-subject mean values of prefrontal cortex oxygen saturation (SO2) were 68.8±3.2% (right) and 71.0±3.6% (left), and of total hemoglobin concentration (tHb) were 69.6±9.6 µM (right) and 69.5±9.9 µM (left). The typical cortical activation response to the cognitive task [characterized by an increase in oxyhemoglobin (O2Hb) with a concurrent decrease in deoxyhemoglobin (HHb)] at each measurement point is observed in only four subjects. In this subset, the amplitude of the O2Hb increase and HHb decrease is uniform over each prefrontal cortex area and comparable between the two hemispheres. These findings agree with previous studies using continuous wave functional near-IR spectroscopy and functional magnetic resonance imaging, therefore demonstrating the potential of a time-resolved spectroscopy approach. In addition, a significant increase in SO2 levels was observed in the right (1.1±0.5%) compared to left side of the prefrontal cortex (0.9±0.5%) (P=0.005). A different pattern of cortical activation (characterized by the lack of HHb decrease or even increased HHb) was observed in the remaining subjects." @default.
- W2031146519 created "2016-06-24" @default.
- W2031146519 creator A5004522727 @default.
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- W2031146519 date "2005-01-01" @default.
- W2031146519 modified "2023-10-15" @default.
- W2031146519 title "Bilateral prefrontal cortex oxygenation responses to a verbal fluency task: a multichannel time-resolved near-infrared topography study" @default.
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- W2031146519 doi "https://doi.org/10.1117/1.1851512" @default.
- W2031146519 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15847578" @default.
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