Matches in SemOpenAlex for { <https://semopenalex.org/work/W2031170418> ?p ?o ?g. }
- W2031170418 endingPage "261" @default.
- W2031170418 startingPage "256" @default.
- W2031170418 abstract "Purpose of review Mycophenolate mofetil (MMF) is an alternative to cyclophosphamide for the treatment of lupus nephritis. The precise role of MMF is under ongoing evaluation. This review provides an up-to-date summary of MMF and its use as remission induction and maintenance therapy for lupus nephritis. Recent findings For remission induction, recent randomized trial data suggest that MMF is at least as good as intravenous cyclophosphamide in terms of efficacy and safety. MMF may have superior efficacy to intravenous cyclophosphamide in black populations. Preliminary data suggest that MMF with tacrolimus may have added benefit over cyclophosphamide. For remission maintenance, limited evidence suggests that MMF is superior to quarterly intravenous cyclophosphamide and equivalent to azathioprine. Summary MMF is likely to be noninferior to cyclophosphamide for the induction of remission in lupus nephritis. Early results suggest that MMF is equivalent to azathioprine for remission maintenance, although large randomized trial data are awaited to clarify the role. The optimal dosing strategy and duration of MMF treatment have not been established. The efficacy and safety of MMF in patients with severe renal impairment requires further investigation. Longer follow-up is required to fully assess the impact of MMF on renal survival and overall mortality." @default.
- W2031170418 created "2016-06-24" @default.
- W2031170418 creator A5001067070 @default.
- W2031170418 creator A5013696488 @default.
- W2031170418 creator A5068686993 @default.
- W2031170418 date "2009-05-01" @default.
- W2031170418 modified "2023-10-17" @default.
- W2031170418 title "What is the value of mycophenolate mofetil as induction and maintenance therapy in lupus nephritis?" @default.
- W2031170418 cites W1489790705 @default.
- W2031170418 cites W1526833570 @default.
- W2031170418 cites W1586534080 @default.
- W2031170418 cites W1782008537 @default.
- W2031170418 cites W1890638053 @default.
- W2031170418 cites W1891570058 @default.
- W2031170418 cites W193850055 @default.
- W2031170418 cites W1971058219 @default.
- W2031170418 cites W1987922228 @default.
- W2031170418 cites W1995532582 @default.
- W2031170418 cites W1996470340 @default.
- W2031170418 cites W2005229698 @default.
- W2031170418 cites W2005953407 @default.
- W2031170418 cites W2010416599 @default.
- W2031170418 cites W2014957162 @default.
- W2031170418 cites W2016100084 @default.
- W2031170418 cites W2024442997 @default.
- W2031170418 cites W2039759404 @default.
- W2031170418 cites W2045139782 @default.
- W2031170418 cites W2046088757 @default.
- W2031170418 cites W2048340159 @default.
- W2031170418 cites W2048350130 @default.
- W2031170418 cites W2049831025 @default.
- W2031170418 cites W2055962331 @default.
- W2031170418 cites W2061744808 @default.
- W2031170418 cites W2064342954 @default.
- W2031170418 cites W2065201007 @default.
- W2031170418 cites W2079303074 @default.
- W2031170418 cites W2089150380 @default.
- W2031170418 cites W2094074845 @default.
- W2031170418 cites W2096194879 @default.
- W2031170418 cites W2099244192 @default.
- W2031170418 cites W2103051735 @default.
- W2031170418 cites W2111940985 @default.
- W2031170418 cites W2122338150 @default.
- W2031170418 cites W2123602540 @default.
- W2031170418 cites W2128459490 @default.
- W2031170418 cites W2134214128 @default.
- W2031170418 cites W2135212798 @default.
- W2031170418 cites W2135881786 @default.
- W2031170418 cites W2141502494 @default.
- W2031170418 cites W2144774241 @default.
- W2031170418 cites W2148306888 @default.
- W2031170418 cites W2149093312 @default.
- W2031170418 cites W2149882694 @default.
- W2031170418 cites W2150064963 @default.
- W2031170418 cites W2151072497 @default.
- W2031170418 cites W2153689462 @default.
- W2031170418 cites W2158657596 @default.
- W2031170418 cites W2160388191 @default.
- W2031170418 cites W2160773404 @default.
- W2031170418 cites W2171454376 @default.
- W2031170418 cites W2321360678 @default.
- W2031170418 cites W2325870812 @default.
- W2031170418 cites W2336236972 @default.
- W2031170418 cites W3156996711 @default.
- W2031170418 cites W4214677758 @default.
- W2031170418 cites W50336179 @default.
- W2031170418 doi "https://doi.org/10.1097/bor.0b013e32832a0698" @default.
- W2031170418 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19399995" @default.
- W2031170418 hasPublicationYear "2009" @default.
- W2031170418 type Work @default.
- W2031170418 sameAs 2031170418 @default.
- W2031170418 citedByCount "16" @default.
- W2031170418 countsByYear W20311704182012 @default.
- W2031170418 countsByYear W20311704182019 @default.
- W2031170418 crossrefType "journal-article" @default.
- W2031170418 hasAuthorship W2031170418A5001067070 @default.
- W2031170418 hasAuthorship W2031170418A5013696488 @default.
- W2031170418 hasAuthorship W2031170418A5068686993 @default.
- W2031170418 hasConcept C126322002 @default.
- W2031170418 hasConcept C168563851 @default.
- W2031170418 hasConcept C2776694085 @default.
- W2031170418 hasConcept C2776755627 @default.
- W2031170418 hasConcept C2776760755 @default.
- W2031170418 hasConcept C2776912625 @default.
- W2031170418 hasConcept C2777288759 @default.
- W2031170418 hasConcept C2778283404 @default.
- W2031170418 hasConcept C2779134260 @default.
- W2031170418 hasConcept C2779912601 @default.
- W2031170418 hasConcept C2909675724 @default.
- W2031170418 hasConcept C2909935303 @default.
- W2031170418 hasConcept C2911091166 @default.
- W2031170418 hasConcept C71924100 @default.
- W2031170418 hasConceptScore W2031170418C126322002 @default.
- W2031170418 hasConceptScore W2031170418C168563851 @default.
- W2031170418 hasConceptScore W2031170418C2776694085 @default.
- W2031170418 hasConceptScore W2031170418C2776755627 @default.
- W2031170418 hasConceptScore W2031170418C2776760755 @default.
- W2031170418 hasConceptScore W2031170418C2776912625 @default.