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- W2031178098 abstract "The Argentine HIV-1 epidemic is considered to be represented mainly by subtype B and diverse B/F recombinants, with apparent absence of pure subtype F. In this study we describe three novel HIV-1 variants isolated from four infants born in different and distant provinces of Argentina. Partial analysis of different gene fragments spanning 18.5–40.8% of the HIV-1 complete genome revealed two subtype A HIV-1 strains in siblings, a B/C recombinant with a novel mosaic structure, and a putative subtype F. Characteristic patterns of genomic and amino acid sequences of the newly reported subtype F isolate suggest a closer genetic relationship to Argentine B/F recombinants than any other subtype F strain described so far, while the A and B/C subtypes found correspond to unusual genotypes in Argentina. Understanding the origin, diversity, and spread of HIV-1 strains worldwide will be necessary for the development of an effective vaccine approach." @default.
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- W2031178098 date "2005-02-01" @default.
- W2031178098 modified "2023-09-27" @default.
- W2031178098 title "Circulation of Novel HIV Type 1 A, B/C, and F Subtypes in Argentina" @default.
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- W2031178098 doi "https://doi.org/10.1089/aid.2005.21.158" @default.
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