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- W2031207785 abstract "We found, by an in situ hybridization method with riboprobes synthesized from human cDNA of the retinoic acid receptor (RAR), that the RAR genes (predominantly gamma-subtype) are intensively expressed in the epidermis of normal and psoriasic human skins, and also in keratinizing fronts of 4-day-old mouse skins, nail matrices and hair follicles. Thus, target cells of retinoic acid in the skins are concluded to be keratinocytes, which is quite consistent with the fact that retinoic acid regulates keratinization of epidermis in vivo and also modulates expression of the keratin gene in vitro." @default.
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- W2031207785 date "1989-12-18" @default.
- W2031207785 modified "2023-10-14" @default.
- W2031207785 title "Expression of retinoic acid receptor genes in keratinizing front of skin" @default.
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- W2031207785 doi "https://doi.org/10.1016/0014-5793(89)81501-7" @default.
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