Matches in SemOpenAlex for { <https://semopenalex.org/work/W2031226833> ?p ?o ?g. }
- W2031226833 endingPage "134" @default.
- W2031226833 startingPage "126" @default.
- W2031226833 abstract "The effect of membrane binding on the structure and stability of the cytotoxin α-sarcin has been studied by differential scanning calorimetry, Fourier-transform infrared and fluorescence spectroscopic techniques. The thermal unfolding of α-sarcin in aqueous solution fits into a two-state transition characterized by a transition temperature (Tm) of 52.6°C and a calorimetric enthalpy (ΔHcal) of 136 kcal/mol. Upon interaction with phosphatidylglycerol vesicles, α-sarcin undergoes conformational changes, as deduced from the FTIR and fluorescence emission spectra. These changes result in a decreased Tm and ΔHcal values for the thermal unfolding of phospholipid-bound α-sarcin. The lower Tm value for lipid-bound α-sarcin is also observed at the level of secondary and tertiary structures, based on analyses of both the amide I′ infrared spectrum and the tryptophan emission of the protein as a function of temperature, respectively. The results obtained indicate a protein destabilization promoted by the phospholipid interaction." @default.
- W2031226833 created "2016-06-24" @default.
- W2031226833 creator A5005783840 @default.
- W2031226833 creator A5025375215 @default.
- W2031226833 creator A5058686844 @default.
- W2031226833 creator A5071698672 @default.
- W2031226833 creator A5073268079 @default.
- W2031226833 creator A5075440328 @default.
- W2031226833 creator A5075612265 @default.
- W2031226833 creator A5076774827 @default.
- W2031226833 date "1995-09-01" @default.
- W2031226833 modified "2023-10-11" @default.
- W2031226833 title "Thermal unfolding of the cytotoxin α-sarcin: phospholipid binding induces destabilization of the protein structure" @default.
- W2031226833 cites W1437642699 @default.
- W2031226833 cites W1496368635 @default.
- W2031226833 cites W1531523283 @default.
- W2031226833 cites W1536128836 @default.
- W2031226833 cites W1585363411 @default.
- W2031226833 cites W1606451505 @default.
- W2031226833 cites W1791461757 @default.
- W2031226833 cites W1838264472 @default.
- W2031226833 cites W1963773907 @default.
- W2031226833 cites W1963827027 @default.
- W2031226833 cites W1965522811 @default.
- W2031226833 cites W1969741344 @default.
- W2031226833 cites W1974189780 @default.
- W2031226833 cites W1984675243 @default.
- W2031226833 cites W1987387737 @default.
- W2031226833 cites W1990236081 @default.
- W2031226833 cites W1991584379 @default.
- W2031226833 cites W1994417790 @default.
- W2031226833 cites W2003148198 @default.
- W2031226833 cites W2005231522 @default.
- W2031226833 cites W2014537859 @default.
- W2031226833 cites W2025494960 @default.
- W2031226833 cites W2033518683 @default.
- W2031226833 cites W2034457202 @default.
- W2031226833 cites W2045497635 @default.
- W2031226833 cites W2045517108 @default.
- W2031226833 cites W2045540829 @default.
- W2031226833 cites W2050200950 @default.
- W2031226833 cites W2050566440 @default.
- W2031226833 cites W2063164023 @default.
- W2031226833 cites W2071195326 @default.
- W2031226833 cites W2082025710 @default.
- W2031226833 cites W2086780919 @default.
- W2031226833 cites W2088107416 @default.
- W2031226833 cites W2132860695 @default.
- W2031226833 cites W2134880328 @default.
- W2031226833 cites W2159392498 @default.
- W2031226833 cites W2175913572 @default.
- W2031226833 cites W2177743694 @default.
- W2031226833 cites W2217579908 @default.
- W2031226833 cites W28039676 @default.
- W2031226833 cites W296432340 @default.
- W2031226833 cites W4239966236 @default.
- W2031226833 doi "https://doi.org/10.1016/0167-4838(95)00100-9" @default.
- W2031226833 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7548154" @default.
- W2031226833 hasPublicationYear "1995" @default.
- W2031226833 type Work @default.
- W2031226833 sameAs 2031226833 @default.
- W2031226833 citedByCount "16" @default.
- W2031226833 countsByYear W20312268332015 @default.
- W2031226833 countsByYear W20312268332016 @default.
- W2031226833 countsByYear W20312268332019 @default.
- W2031226833 countsByYear W20312268332020 @default.
- W2031226833 countsByYear W20312268332022 @default.
- W2031226833 crossrefType "journal-article" @default.
- W2031226833 hasAuthorship W2031226833A5005783840 @default.
- W2031226833 hasAuthorship W2031226833A5025375215 @default.
- W2031226833 hasAuthorship W2031226833A5058686844 @default.
- W2031226833 hasAuthorship W2031226833A5071698672 @default.
- W2031226833 hasAuthorship W2031226833A5073268079 @default.
- W2031226833 hasAuthorship W2031226833A5075440328 @default.
- W2031226833 hasAuthorship W2031226833A5075612265 @default.
- W2031226833 hasAuthorship W2031226833A5076774827 @default.
- W2031226833 hasConcept C113196181 @default.
- W2031226833 hasConcept C121332964 @default.
- W2031226833 hasConcept C130316041 @default.
- W2031226833 hasConcept C147789679 @default.
- W2031226833 hasConcept C160892712 @default.
- W2031226833 hasConcept C184651966 @default.
- W2031226833 hasConcept C185592680 @default.
- W2031226833 hasConcept C2776706248 @default.
- W2031226833 hasConcept C2778918659 @default.
- W2031226833 hasConcept C39519442 @default.
- W2031226833 hasConcept C41625074 @default.
- W2031226833 hasConcept C43617362 @default.
- W2031226833 hasConcept C515207424 @default.
- W2031226833 hasConcept C55493867 @default.
- W2031226833 hasConcept C62520636 @default.
- W2031226833 hasConcept C62614982 @default.
- W2031226833 hasConcept C8010536 @default.
- W2031226833 hasConcept C91881484 @default.
- W2031226833 hasConcept C97355855 @default.
- W2031226833 hasConceptScore W2031226833C113196181 @default.
- W2031226833 hasConceptScore W2031226833C121332964 @default.
- W2031226833 hasConceptScore W2031226833C130316041 @default.