Matches in SemOpenAlex for { <https://semopenalex.org/work/W2031230900> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W2031230900 endingPage "276" @default.
- W2031230900 startingPage "272" @default.
- W2031230900 abstract "Airway smooth muscle (ASM), an important tissue involved in the regulation of bronchomotor tone, exists in the trachea and in the bronchial tree up to the terminal bronchioles. The physiological relevance of ASM in healthy airways remains unclear. Evidence, however, suggests that ASM undergoes marked phenotypic modulation in lung development and in disease states such as asthma, chronic bronchitis and emphysema. The shortening of ASM regulates airway luminal diameter and modulates airway resistance, which can be augmented by cytokines as well as extracellular matrix alterations. ASM may also serve immunomodulatory functions, which are mediated by the secretion of pro-inflammatory mediators such as cytokines and chemokines. In addition, ASM mass increases in chronic airway diseases and may represent either a pathologic or an injury-repair response due to chronic inflammation. This review will present evidence that ASM, a passive tissue, may become an active participant in modulating inflammation in chronic lung diseases. Cell facts 1. Found in the trachea and along the bronchial tree. 2. Critically important in regulating bronchomotor tone of the airways. 3. Differentiation state is associated with the expression of various contractile 4. Displays phenotypic modulation of mechanical, synthetic and proliferative responses. 5. Secretes cytokines, chemokines and extracellular matrix proteins. 6. May serve as a potential new target for the treatment of chronic lung diseases." @default.
- W2031230900 created "2016-06-24" @default.
- W2031230900 creator A5079628483 @default.
- W2031230900 creator A5082888399 @default.
- W2031230900 date "2003-03-01" @default.
- W2031230900 modified "2023-10-17" @default.
- W2031230900 title "Airway smooth muscle: contraction and beyond" @default.
- W2031230900 cites W1849488471 @default.
- W2031230900 cites W1968169817 @default.
- W2031230900 cites W1971667712 @default.
- W2031230900 cites W1972975677 @default.
- W2031230900 cites W1980293900 @default.
- W2031230900 cites W2023370394 @default.
- W2031230900 cites W2031523515 @default.
- W2031230900 cites W2053884940 @default.
- W2031230900 cites W2067028041 @default.
- W2031230900 cites W2115586501 @default.
- W2031230900 cites W2130901740 @default.
- W2031230900 cites W2132958035 @default.
- W2031230900 cites W2135497215 @default.
- W2031230900 cites W2138229835 @default.
- W2031230900 cites W2140033514 @default.
- W2031230900 cites W2150694129 @default.
- W2031230900 cites W2163011809 @default.
- W2031230900 cites W2165016962 @default.
- W2031230900 cites W2165106797 @default.
- W2031230900 cites W2165537590 @default.
- W2031230900 cites W2232019329 @default.
- W2031230900 cites W2273776351 @default.
- W2031230900 cites W2321102167 @default.
- W2031230900 cites W2329413176 @default.
- W2031230900 cites W2336420091 @default.
- W2031230900 cites W2417576966 @default.
- W2031230900 doi "https://doi.org/10.1016/s1357-2725(02)00259-5" @default.
- W2031230900 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12531237" @default.
- W2031230900 hasPublicationYear "2003" @default.
- W2031230900 type Work @default.
- W2031230900 sameAs 2031230900 @default.
- W2031230900 citedByCount "78" @default.
- W2031230900 countsByYear W20312309002012 @default.
- W2031230900 countsByYear W20312309002013 @default.
- W2031230900 countsByYear W20312309002014 @default.
- W2031230900 countsByYear W20312309002015 @default.
- W2031230900 countsByYear W20312309002016 @default.
- W2031230900 countsByYear W20312309002017 @default.
- W2031230900 countsByYear W20312309002018 @default.
- W2031230900 countsByYear W20312309002019 @default.
- W2031230900 countsByYear W20312309002020 @default.
- W2031230900 countsByYear W20312309002021 @default.
- W2031230900 countsByYear W20312309002022 @default.
- W2031230900 countsByYear W20312309002023 @default.
- W2031230900 crossrefType "journal-article" @default.
- W2031230900 hasAuthorship W2031230900A5079628483 @default.
- W2031230900 hasAuthorship W2031230900A5082888399 @default.
- W2031230900 hasConcept C105702510 @default.
- W2031230900 hasConcept C105922876 @default.
- W2031230900 hasConcept C126322002 @default.
- W2031230900 hasConcept C163415756 @default.
- W2031230900 hasConcept C164705383 @default.
- W2031230900 hasConcept C2776050358 @default.
- W2031230900 hasConcept C42219234 @default.
- W2031230900 hasConcept C71924100 @default.
- W2031230900 hasConceptScore W2031230900C105702510 @default.
- W2031230900 hasConceptScore W2031230900C105922876 @default.
- W2031230900 hasConceptScore W2031230900C126322002 @default.
- W2031230900 hasConceptScore W2031230900C163415756 @default.
- W2031230900 hasConceptScore W2031230900C164705383 @default.
- W2031230900 hasConceptScore W2031230900C2776050358 @default.
- W2031230900 hasConceptScore W2031230900C42219234 @default.
- W2031230900 hasConceptScore W2031230900C71924100 @default.
- W2031230900 hasIssue "3" @default.
- W2031230900 hasLocation W20312309001 @default.
- W2031230900 hasOpenAccess W2031230900 @default.
- W2031230900 hasPrimaryLocation W20312309001 @default.
- W2031230900 hasRelatedWork W1993296664 @default.
- W2031230900 hasRelatedWork W1997898322 @default.
- W2031230900 hasRelatedWork W2015127672 @default.
- W2031230900 hasRelatedWork W2048064500 @default.
- W2031230900 hasRelatedWork W2071443315 @default.
- W2031230900 hasRelatedWork W2107780144 @default.
- W2031230900 hasRelatedWork W2120447521 @default.
- W2031230900 hasRelatedWork W2150928563 @default.
- W2031230900 hasRelatedWork W2173315413 @default.
- W2031230900 hasRelatedWork W4249953205 @default.
- W2031230900 hasVolume "35" @default.
- W2031230900 isParatext "false" @default.
- W2031230900 isRetracted "false" @default.
- W2031230900 magId "2031230900" @default.
- W2031230900 workType "article" @default.