FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2031308308> ?p ?o ?g. }

• W2031308308 endingPage "590" @default.
• W2031308308 startingPage "586" @default.
• W2031308308 abstract "Purpose of review Diabetic neuropathy is a debilitating consequence of type 1 and 2 diabetes. Hyperglycemia disrupts the normal function of neurons and their supporting glia at multiple levels. The complexity of this complication, combined with difficulties of delivering therapy to sensory, sympathetic and parasympathetic neurons, contributes to the intractability of this serious diabetic complication. This review summarizes recent reviews examining the state of research on and treatment of diabetic neuropathy and highlights areas of clinical and basic research that may yield new diagnostic and treatment options. Recent findings Recent reviews summarize the effects of hyperglycemia on the peripheral nervous system as well as diagnosis and treatment of patients with diabetic neuropathy. Advances in the analysis of intraepidermal fiber densities could shorten the time course of clinical trials and extend data analyses to include sympathetic as well as sensory information. Unchecked glucose-mediated oxidative stress and advanced glycation endproduct signaling through receptors for advanced glycation endproducts are implicated in diabetic neuropathy and may serve as new therapeutic targets. Summary The best efforts of countless investigators have yet to find effective treatments either to stop the progression of axonal degeneration and cell death or regrow damaged axons. Basic research into the prevention of oxidative stress caused by excess glucose as well as the prevention of advanced glycation endproduct/receptor for advanced glycation endproduct signaling may offer new therapeutic targets. The use of skin biopsies may aid in early detection of both sensory and autonomic neuropathy, and perhaps in the case of patients with type 2 diabetes, diagnose neuropathy prior to the onset of symptoms." @default.
• W2031308308 created "2016-06-24" @default.
• W2031308308 creator A5056304003 @default.
• W2031308308 creator A5064921648 @default.
• W2031308308 date "2005-10-01" @default.
• W2031308308 modified "2023-10-15" @default.
• W2031308308 title "New developments in diabetic neuropathy" @default.
• W2031308308 cites W1503258737 @default.
• W2031308308 cites W1562556996 @default.
• W2031308308 cites W1965049460 @default.
• W2031308308 cites W1965146473 @default.
• W2031308308 cites W1966234811 @default.
• W2031308308 cites W1969539304 @default.
• W2031308308 cites W1970534107 @default.
• W2031308308 cites W1978575651 @default.
• W2031308308 cites W1979005579 @default.
• W2031308308 cites W1981047340 @default.
• W2031308308 cites W1985324043 @default.
• W2031308308 cites W1989490746 @default.
• W2031308308 cites W1996111334 @default.
• W2031308308 cites W2005485195 @default.
• W2031308308 cites W2012373895 @default.
• W2031308308 cites W2013633841 @default.
• W2031308308 cites W2025958954 @default.
• W2031308308 cites W2026983868 @default.
• W2031308308 cites W2030912622 @default.
• W2031308308 cites W2044437167 @default.
• W2031308308 cites W2047106058 @default.
• W2031308308 cites W2048748542 @default.
• W2031308308 cites W2053814042 @default.
• W2031308308 cites W2057421851 @default.
• W2031308308 cites W2061603759 @default.
• W2031308308 cites W2062548885 @default.
• W2031308308 cites W2068504431 @default.
• W2031308308 cites W2075081752 @default.
• W2031308308 cites W2077518063 @default.
• W2031308308 cites W2085384724 @default.
• W2031308308 cites W2085618412 @default.
• W2031308308 cites W2095820351 @default.
• W2031308308 cites W2099615506 @default.
• W2031308308 cites W2119389187 @default.
• W2031308308 cites W2119807178 @default.
• W2031308308 cites W2124098112 @default.
• W2031308308 cites W2140945151 @default.
• W2031308308 cites W2142530587 @default.
• W2031308308 cites W2153789216 @default.
• W2031308308 cites W2160234008 @default.
• W2031308308 cites W2161485411 @default.
• W2031308308 cites W2162666481 @default.
• W2031308308 cites W2164336720 @default.
• W2031308308 cites W2274711340 @default.
• W2031308308 cites W2316993747 @default.
• W2031308308 cites W2439834209 @default.
• W2031308308 cites W2607779897 @default.
• W2031308308 cites W2734011609 @default.
• W2031308308 cites W3022887809 @default.
• W2031308308 cites W4237707841 @default.
• W2031308308 cites W4243861699 @default.
• W2031308308 doi "https://doi.org/10.1097/01.wco.0000178825.56414.52" @default.
• W2031308308 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16155445" @default.
• W2031308308 hasPublicationYear "2005" @default.
• W2031308308 type Work @default.
• W2031308308 sameAs 2031308308 @default.
• W2031308308 citedByCount "64" @default.
• W2031308308 countsByYear W20313083082012 @default.
• W2031308308 countsByYear W20313083082013 @default.
• W2031308308 countsByYear W20313083082014 @default.
• W2031308308 countsByYear W20313083082015 @default.
• W2031308308 countsByYear W20313083082016 @default.
• W2031308308 countsByYear W20313083082017 @default.
• W2031308308 countsByYear W20313083082018 @default.
• W2031308308 countsByYear W20313083082022 @default.
• W2031308308 countsByYear W20313083082023 @default.
• W2031308308 crossrefType "journal-article" @default.
• W2031308308 hasAuthorship W2031308308A5056304003 @default.
• W2031308308 hasAuthorship W2031308308A5064921648 @default.
• W2031308308 hasConcept C126322002 @default.
• W2031308308 hasConcept C134018914 @default.
• W2031308308 hasConcept C147990577 @default.
• W2031308308 hasConcept C169760540 @default.
• W2031308308 hasConcept C2776151105 @default.
• W2031308308 hasConcept C2779178840 @default.
• W2031308308 hasConcept C2779901536 @default.
• W2031308308 hasConcept C535046627 @default.
• W2031308308 hasConcept C555293320 @default.
• W2031308308 hasConcept C60644358 @default.
• W2031308308 hasConcept C71924100 @default.
• W2031308308 hasConcept C81182388 @default.
• W2031308308 hasConcept C86803240 @default.
• W2031308308 hasConceptScore W2031308308C126322002 @default.
• W2031308308 hasConceptScore W2031308308C134018914 @default.
• W2031308308 hasConceptScore W2031308308C147990577 @default.
• W2031308308 hasConceptScore W2031308308C169760540 @default.
• W2031308308 hasConceptScore W2031308308C2776151105 @default.
• W2031308308 hasConceptScore W2031308308C2779178840 @default.
• W2031308308 hasConceptScore W2031308308C2779901536 @default.
• W2031308308 hasConceptScore W2031308308C535046627 @default.
• W2031308308 hasConceptScore W2031308308C555293320 @default.

• next