Matches in SemOpenAlex for { <https://semopenalex.org/work/W2031355616> ?p ?o ?g. }
- W2031355616 endingPage "84" @default.
- W2031355616 startingPage "80" @default.
- W2031355616 abstract "It has been established that leptin displays a number of effects on peripheral tissues. We have investigated the effect of the hormone on lipid synthesis, apolipoprotein biogenesis and lipoprotein secretion in Caco-2 cells. Immunocytochemistry revealed the presence of leptin receptors (Ob-Rb) on the basolateral membrane. Incubation of cells with 200 nM leptin resulted in a decreased export of triglycerides in the basolateral medium without affecting monoglyceride, diglyceride and cholesterol ester lipid classes. It also significantly reduced the output of de novo-synthesized apolipoprotein (Apo)B-100 and ApoB-48 as well as that of newly formed chylomicrons and of low-density lipoproteins. It also enhanced that of ApoA-I, ApoA-IV and ApoE. Our results support the hypothesis that leptin can affect energy balance at the gut level by reducing lipid release into the circulation." @default.
- W2031355616 created "2016-06-24" @default.
- W2031355616 creator A5005178255 @default.
- W2031355616 creator A5020808506 @default.
- W2031355616 creator A5029335213 @default.
- W2031355616 creator A5040055543 @default.
- W2031355616 creator A5042131851 @default.
- W2031355616 creator A5078702171 @default.
- W2031355616 creator A5085781030 @default.
- W2031355616 creator A5087719523 @default.
- W2031355616 date "2001-11-09" @default.
- W2031355616 modified "2023-09-25" @default.
- W2031355616 title "Effect of human recombinant leptin on lipid handling by fully differentiated Caco-2 cells" @default.
- W2031355616 cites W1528470195 @default.
- W2031355616 cites W1748872362 @default.
- W2031355616 cites W1775749144 @default.
- W2031355616 cites W1900852307 @default.
- W2031355616 cites W1964852585 @default.
- W2031355616 cites W1968666103 @default.
- W2031355616 cites W1981660336 @default.
- W2031355616 cites W1985604583 @default.
- W2031355616 cites W1993281511 @default.
- W2031355616 cites W1996713062 @default.
- W2031355616 cites W2001422145 @default.
- W2031355616 cites W2004861927 @default.
- W2031355616 cites W2005714993 @default.
- W2031355616 cites W2009265787 @default.
- W2031355616 cites W2012099782 @default.
- W2031355616 cites W2014093920 @default.
- W2031355616 cites W2025846514 @default.
- W2031355616 cites W2035754392 @default.
- W2031355616 cites W2048078221 @default.
- W2031355616 cites W2057982162 @default.
- W2031355616 cites W2059063316 @default.
- W2031355616 cites W2066382986 @default.
- W2031355616 cites W2068510129 @default.
- W2031355616 cites W2074396592 @default.
- W2031355616 cites W2087133453 @default.
- W2031355616 cites W2090977677 @default.
- W2031355616 cites W2104644353 @default.
- W2031355616 cites W2104757182 @default.
- W2031355616 cites W2125510262 @default.
- W2031355616 cites W2148844770 @default.
- W2031355616 cites W2186016574 @default.
- W2031355616 cites W2315769937 @default.
- W2031355616 cites W2334337188 @default.
- W2031355616 cites W2412616679 @default.
- W2031355616 cites W4212881722 @default.
- W2031355616 doi "https://doi.org/10.1016/s0014-5793(01)03032-0" @default.
- W2031355616 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11707272" @default.
- W2031355616 hasPublicationYear "2001" @default.
- W2031355616 type Work @default.
- W2031355616 sameAs 2031355616 @default.
- W2031355616 citedByCount "31" @default.
- W2031355616 countsByYear W20313556162012 @default.
- W2031355616 countsByYear W20313556162013 @default.
- W2031355616 countsByYear W20313556162014 @default.
- W2031355616 countsByYear W20313556162015 @default.
- W2031355616 countsByYear W20313556162016 @default.
- W2031355616 countsByYear W20313556162018 @default.
- W2031355616 countsByYear W20313556162020 @default.
- W2031355616 countsByYear W20313556162021 @default.
- W2031355616 crossrefType "journal-article" @default.
- W2031355616 hasAuthorship W2031355616A5005178255 @default.
- W2031355616 hasAuthorship W2031355616A5020808506 @default.
- W2031355616 hasAuthorship W2031355616A5029335213 @default.
- W2031355616 hasAuthorship W2031355616A5040055543 @default.
- W2031355616 hasAuthorship W2031355616A5042131851 @default.
- W2031355616 hasAuthorship W2031355616A5078702171 @default.
- W2031355616 hasAuthorship W2031355616A5085781030 @default.
- W2031355616 hasAuthorship W2031355616A5087719523 @default.
- W2031355616 hasBestOaLocation W20313556161 @default.
- W2031355616 hasConcept C11772777 @default.
- W2031355616 hasConcept C126322002 @default.
- W2031355616 hasConcept C134018914 @default.
- W2031355616 hasConcept C14372207 @default.
- W2031355616 hasConcept C1491633281 @default.
- W2031355616 hasConcept C170493617 @default.
- W2031355616 hasConcept C185592680 @default.
- W2031355616 hasConcept C193176779 @default.
- W2031355616 hasConcept C2778163477 @default.
- W2031355616 hasConcept C2780072125 @default.
- W2031355616 hasConcept C2780613262 @default.
- W2031355616 hasConcept C43554185 @default.
- W2031355616 hasConcept C511355011 @default.
- W2031355616 hasConcept C55493867 @default.
- W2031355616 hasConcept C62746215 @default.
- W2031355616 hasConcept C71924100 @default.
- W2031355616 hasConcept C8243546 @default.
- W2031355616 hasConcept C86803240 @default.
- W2031355616 hasConceptScore W2031355616C11772777 @default.
- W2031355616 hasConceptScore W2031355616C126322002 @default.
- W2031355616 hasConceptScore W2031355616C134018914 @default.
- W2031355616 hasConceptScore W2031355616C14372207 @default.
- W2031355616 hasConceptScore W2031355616C1491633281 @default.
- W2031355616 hasConceptScore W2031355616C170493617 @default.
- W2031355616 hasConceptScore W2031355616C185592680 @default.
- W2031355616 hasConceptScore W2031355616C193176779 @default.