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- W2031371479 abstract "Several autocrine and paracrine growth factor circuits have been found in human rhabdomyosarcoma cells. In this study we show that endothelin-3 (ET-3), a vasoactive peptide, is produced by human rhabdomyosarcoma cell lines, whereas it is not expressed by human sarcoma cell lines of non-muscle origin. We did not find evidence of a significant autocrine loop; nevertheless ET-3 produced by rhabdomyosarcoma cells can act as a paracrine factor, since it promotes migration of endothelial cells. Moreover ET-3 is present in plasma of mice bearing xenografts of human rhabdomyosarcoma cells, and may be potential new marker of the human rhabdomyosarcoma to be studied further." @default.
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- W2031371479 date "2006-03-01" @default.
- W2031371479 modified "2023-09-25" @default.
- W2031371479 title "Endothelin-3 production by human rhabdomyosarcoma: A possible new marker with a paracrine role" @default.
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- W2031371479 doi "https://doi.org/10.1016/j.ejca.2005.11.024" @default.
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