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• W2031400878 abstract "A novel approach to incorporate the macrocyclic rings onto the privileged substructure, i.e., tetrahydroquinoline scaffold, is developed. The presence of an amino acid-derived moiety in the macrocyclic skeleton provides an opportunity to modulate the nature of the chiral side chain. Further, evaluation in a zebrafish screen identified three active small molecules (2.5b, 3.2d, and 4.2) as antiangiogenesis agents at 2.5 μM." @default.
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• W2031400878 date "2013-05-30" @default.
• W2031400878 modified "2023-10-01" @default.
• W2031400878 title "Tetrahydroquinoline-Derived Macrocyclic Toolbox: The Discovery of Antiangiogenesis Agents in Zebrafish Assay" @default.
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• W2031400878 doi "https://doi.org/10.1021/ml400026n" @default.
• W2031400878 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4027127" @default.
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