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- W2031462124 abstract "Human cytochrome c oxidase (COX) is a complex of 13 subunits: three are encoded by mitochondrial DNA and ten by nuclear DNA. We have now isolated a full-length cDNA specifying subunit VIIb, the last remaining uncharacterized nuclear-encoded subunit cDNA of human COX. The cDNA encodes a deduced 80-aa polypeptide, including a 24-amino acid (aa) N-terminal leader sequence and a 56-aa mature polypeptide with 82% identity to mature bovine COX VIIb. Southern blot hybridization of human muscle genomic DNA showed multiple hybridizing bands, implying the presence of a large coxVIIb gene family, including a potential processed pseudogene." @default.
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- W2031462124 date "1993-02-01" @default.
- W2031462124 modified "2023-09-27" @default.
- W2031462124 title "Isolation of a cDNA specifying subunit VIIb of human cytochrome c oxidase" @default.
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- W2031462124 doi "https://doi.org/10.1016/0167-4781(93)90301-s" @default.
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