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• W2031482870 abstract "Differential pulse voltammetry with electrochemically treated carbon fiber electrodes was used to study, in anesthetized rats, the alterations of the striatal electrochemical signal appearing at + 300 mV (peak 3), following pharmacological manipulation of the animals. Decreases in peak 3 were obtained after injections of NSD 1015, Ro 4-4602 and Clorgyline. This, in conjunction with biochemical measurements, suggested that 5-hydroxyindolacetic acid (5-HIAA) is, to a considerable extent, responsible for this electrochemical signal. Increases in peak 3 obtained after reserpine, L-tryptophan and D,L-5-HTP, as well as biochemical data reinforced this hypothesis, as did the detection of peak 3 in cerebrospinal fluid and its increase after probenecid injection. The occurrence of a feed-back mechanism is discussed following injection of D,L-5-HTP." @default.
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• W2031482870 date "1981-11-01" @default.
• W2031482870 modified "2023-10-10" @default.
• W2031482870 title "Differential pulse voltammetry in brain tissue. II. Detection of 5-hydroxyindolacetic acid in the rat striatum" @default.
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• W2031482870 doi "https://doi.org/10.1016/0006-8993(81)91143-4" @default.
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