FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2031492431> ?p ?o ?g. }

• W2031492431 endingPage "289" @default.
• W2031492431 startingPage "289" @default.
• W2031492431 abstract "Background: The present investigation evaluates the hepatoprotective and in vitro antioxidant effect of methanolic extract and its isolated constituent, dehydroabietylamine, in Carthamus tinctorious L, var Annigeri-2-, an oil yielding crop. Materials and Methods: The hepatoprotective effects were estimated for the parameters viz, total bilirubin, total protein, serum alanine amino transaminase (ALT) and serum aspartate aminotransferase (AST) and alkaline phosphatase (ALP) and along with the pathological findings of hepatotoxicity. The in vitro antioxidant activity was evaluated by using free radical scavenging assays: DPPH, nitric oxide radical scavenging, hydroxyl radical, reducing power, ferrous ion chelating ability and total antioxidant capacity. Results: Both the methanolic extract (at 150 and 300 mg/kg bw) and dehydroabietylamine (at 50 mg/kg bw) showed significant liver protection against CCl 4 -induced liver damage that was comparable with the standard drug, silymarin (100 mg/kg bw), in reducing the elevated serum enzyme markers. The liver sections of the animals treated with dehydroabietylamine elicit a significant liver protection compared with the methanolic extract against CCl 4 -induced liver damage. Further, both the methanolic extract and dehydroabietylamine exhibited a considerable and dose-dependent scavenging activity of DPPH, nitric oxide and hydroxyl radical. Similarly, in the reducing power assay, the results were very persuasive. In addition, the Fe 2+ chelating activity and the total antioxidant assay established the antioxidant property of the methanolic extract and its isolated constituent. Among the two experimental samples, dehydroabietylamine proved to be more effective for the said parameters. Conclusion: The potent antioxidant and its correlative hepatoprotective activity of the methanolic extract and isolated constituent dehydroabietylamine is therefore attributed to its antioxidant and free radical scavenging activities." @default.
• W2031492431 created "2016-06-24" @default.
• W2031492431 creator A5037502426 @default.
• W2031492431 creator A5041190654 @default.
• W2031492431 creator A5043144161 @default.
• W2031492431 creator A5078088379 @default.
• W2031492431 creator A5070369143 @default.
• W2031492431 date "2011-01-01" @default.
• W2031492431 modified "2023-10-04" @default.
• W2031492431 title "Hepatoprotective and in vitro antioxidant effect of Carthamus tinctorious L, var Annigeri-2-, an oil-yielding crop, against CCl₄-induced liver injury in rats" @default.
• W2031492431 cites W1033420115 @default.
• W2031492431 cites W12387002 @default.
• W2031492431 cites W1540384225 @default.
• W2031492431 cites W1552284165 @default.
• W2031492431 cites W1554188337 @default.
• W2031492431 cites W1771441866 @default.
• W2031492431 cites W1966471687 @default.
• W2031492431 cites W1969471867 @default.
• W2031492431 cites W1971351211 @default.
• W2031492431 cites W1982518099 @default.
• W2031492431 cites W1986937688 @default.
• W2031492431 cites W1992318999 @default.
• W2031492431 cites W1993034915 @default.
• W2031492431 cites W1995316081 @default.
• W2031492431 cites W1998402445 @default.
• W2031492431 cites W2008751043 @default.
• W2031492431 cites W2013258674 @default.
• W2031492431 cites W2013673770 @default.
• W2031492431 cites W2021995332 @default.
• W2031492431 cites W2024716555 @default.
• W2031492431 cites W2054373905 @default.
• W2031492431 cites W2065853716 @default.
• W2031492431 cites W2077013120 @default.
• W2031492431 cites W2080046735 @default.
• W2031492431 cites W2088106473 @default.
• W2031492431 cites W2088851567 @default.
• W2031492431 cites W2092100177 @default.
• W2031492431 cites W2146156288 @default.
• W2031492431 cites W2146668901 @default.
• W2031492431 cites W2171293292 @default.
• W2031492431 cites W2185992664 @default.
• W2031492431 cites W2252938894 @default.
• W2031492431 cites W2263023695 @default.
• W2031492431 cites W2280741230 @default.
• W2031492431 cites W2321806947 @default.
• W2031492431 cites W2324907701 @default.
• W2031492431 cites W2470283956 @default.
• W2031492431 cites W30248127 @default.
• W2031492431 cites W334206998 @default.
• W2031492431 doi "https://doi.org/10.4103/0973-1296.90406" @default.
• W2031492431 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3261062" @default.
• W2031492431 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22262931" @default.
• W2031492431 hasPublicationYear "2011" @default.
• W2031492431 type Work @default.
• W2031492431 sameAs 2031492431 @default.
• W2031492431 citedByCount "17" @default.
• W2031492431 countsByYear W20314924312013 @default.
• W2031492431 countsByYear W20314924312014 @default.
• W2031492431 countsByYear W20314924312015 @default.
• W2031492431 countsByYear W20314924312016 @default.
• W2031492431 countsByYear W20314924312017 @default.
• W2031492431 countsByYear W20314924312020 @default.
• W2031492431 countsByYear W20314924312021 @default.
• W2031492431 countsByYear W20314924312023 @default.
• W2031492431 crossrefType "journal-article" @default.
• W2031492431 hasAuthorship W2031492431A5037502426 @default.
• W2031492431 hasAuthorship W2031492431A5041190654 @default.
• W2031492431 hasAuthorship W2031492431A5043144161 @default.
• W2031492431 hasAuthorship W2031492431A5070369143 @default.
• W2031492431 hasAuthorship W2031492431A5078088379 @default.
• W2031492431 hasBestOaLocation W20314924312 @default.
• W2031492431 hasConcept C160160445 @default.
• W2031492431 hasConcept C178790620 @default.
• W2031492431 hasConcept C181199279 @default.
• W2031492431 hasConcept C185592680 @default.
• W2031492431 hasConcept C2776637226 @default.
• W2031492431 hasConcept C2776778087 @default.
• W2031492431 hasConcept C2776877979 @default.
• W2031492431 hasConcept C2778004101 @default.
• W2031492431 hasConcept C2781401929 @default.
• W2031492431 hasConcept C2781451173 @default.
• W2031492431 hasConcept C519581460 @default.
• W2031492431 hasConcept C55493867 @default.
• W2031492431 hasConcept C556039675 @default.
• W2031492431 hasConcept C71924100 @default.
• W2031492431 hasConcept C98274493 @default.
• W2031492431 hasConceptScore W2031492431C160160445 @default.
• W2031492431 hasConceptScore W2031492431C178790620 @default.
• W2031492431 hasConceptScore W2031492431C181199279 @default.
• W2031492431 hasConceptScore W2031492431C185592680 @default.
• W2031492431 hasConceptScore W2031492431C2776637226 @default.
• W2031492431 hasConceptScore W2031492431C2776778087 @default.
• W2031492431 hasConceptScore W2031492431C2776877979 @default.
• W2031492431 hasConceptScore W2031492431C2778004101 @default.
• W2031492431 hasConceptScore W2031492431C2781401929 @default.
• W2031492431 hasConceptScore W2031492431C2781451173 @default.
• W2031492431 hasConceptScore W2031492431C519581460 @default.
• W2031492431 hasConceptScore W2031492431C55493867 @default.

• next