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• W2031536411 abstract "Successful axon regeneration depends on the expression of regeneration-associated genes by axotomized neurons. Here, we demonstrate, for the first time to our knowledge, the expression of regeneration-associated genes by axotomized human CNS neurons. In situ hybridization and immunohistochemistry showed a transient induction of GAP-43 and c-jun in Clarke's nucleus neurons caudal to traumatic human spinal cord injury. These results support experimental data that nonregenerating central nervous system neurons can temporarily upregulate regeneration-associated genes, reflecting a transient regenerative capacity that fails over time." @default.
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• W2031536411 date "2003-09-24" @default.
• W2031536411 modified "2023-10-17" @default.
• W2031536411 title "Retrograde reactions of Clarke's nucleus neurons after human spinal cord injury" @default.
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• W2031536411 doi "https://doi.org/10.1002/ana.10724" @default.
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