Matches in SemOpenAlex for { <https://semopenalex.org/work/W2031552852> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W2031552852 endingPage "2344" @default.
- W2031552852 startingPage "2337" @default.
- W2031552852 abstract "Rift Valley fever virus (RVFV), a member of the family Bunyaviridae, causes severe to fatal disease in newborn ruminants, as well as abortions in pregnant animals; both preventable by vaccination. Availability of a challenge model is a pre-requisite for vaccine efficacy trials. Several modes of inoculation with RVFV ZH501 were tested on goats and sheep. Differences in development of infectious viremia were observed between animals inoculated with RVFV produced in mosquito C6/36 cells compared to Vero E6 cell-produced inoculum. Only C6/36-RVFV inoculation led to development of viremia in all inoculated sheep and goats. The C6/36 cell-produced RVFV appeared to be more infectious with earlier onset of viremia, especially in sheep, and may also more closely represent a field situation. Goats were somewhat more resistant to the disease development with lower and shorter infectious virus viremia, and with only some animals developing transient increase in rectal temperature in contrast to sheep. In conclusion, a challenge protocol suitable for goat and sheep vaccine efficacy studies was developed using subcutaneous inoculation of 107 PFU per animal with RVFV ZH501 produced in C6/36 cells." @default.
- W2031552852 created "2016-06-24" @default.
- W2031552852 creator A5003585509 @default.
- W2031552852 creator A5009100780 @default.
- W2031552852 creator A5033045614 @default.
- W2031552852 creator A5086821234 @default.
- W2031552852 date "2014-04-01" @default.
- W2031552852 modified "2023-09-27" @default.
- W2031552852 title "Development of a Rift Valley fever virus viremia challenge model in sheep and goats" @default.
- W2031552852 cites W1964141552 @default.
- W2031552852 cites W1978398902 @default.
- W2031552852 cites W2005998481 @default.
- W2031552852 cites W2008230920 @default.
- W2031552852 cites W2010037829 @default.
- W2031552852 cites W2014413376 @default.
- W2031552852 cites W2025692826 @default.
- W2031552852 cites W2032776914 @default.
- W2031552852 cites W2036628368 @default.
- W2031552852 cites W2041415746 @default.
- W2031552852 cites W2053958361 @default.
- W2031552852 cites W2058539210 @default.
- W2031552852 cites W2068748104 @default.
- W2031552852 cites W2089408624 @default.
- W2031552852 cites W2091095379 @default.
- W2031552852 cites W2127081791 @default.
- W2031552852 cites W2137533253 @default.
- W2031552852 cites W2147060534 @default.
- W2031552852 cites W2150120689 @default.
- W2031552852 cites W2155754702 @default.
- W2031552852 cites W2169898965 @default.
- W2031552852 cites W2186630676 @default.
- W2031552852 cites W2412232512 @default.
- W2031552852 cites W2421074544 @default.
- W2031552852 doi "https://doi.org/10.1016/j.vaccine.2014.02.066" @default.
- W2031552852 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24631070" @default.
- W2031552852 hasPublicationYear "2014" @default.
- W2031552852 type Work @default.
- W2031552852 sameAs 2031552852 @default.
- W2031552852 citedByCount "24" @default.
- W2031552852 countsByYear W20315528522015 @default.
- W2031552852 countsByYear W20315528522016 @default.
- W2031552852 countsByYear W20315528522017 @default.
- W2031552852 countsByYear W20315528522018 @default.
- W2031552852 countsByYear W20315528522019 @default.
- W2031552852 countsByYear W20315528522020 @default.
- W2031552852 countsByYear W20315528522022 @default.
- W2031552852 countsByYear W20315528522023 @default.
- W2031552852 crossrefType "journal-article" @default.
- W2031552852 hasAuthorship W2031552852A5003585509 @default.
- W2031552852 hasAuthorship W2031552852A5009100780 @default.
- W2031552852 hasAuthorship W2031552852A5033045614 @default.
- W2031552852 hasAuthorship W2031552852A5086821234 @default.
- W2031552852 hasBestOaLocation W20315528521 @default.
- W2031552852 hasConcept C159047783 @default.
- W2031552852 hasConcept C180032290 @default.
- W2031552852 hasConcept C203014093 @default.
- W2031552852 hasConcept C2522874641 @default.
- W2031552852 hasConcept C2776185481 @default.
- W2031552852 hasConcept C2778960357 @default.
- W2031552852 hasConcept C42972112 @default.
- W2031552852 hasConcept C71924100 @default.
- W2031552852 hasConcept C86803240 @default.
- W2031552852 hasConceptScore W2031552852C159047783 @default.
- W2031552852 hasConceptScore W2031552852C180032290 @default.
- W2031552852 hasConceptScore W2031552852C203014093 @default.
- W2031552852 hasConceptScore W2031552852C2522874641 @default.
- W2031552852 hasConceptScore W2031552852C2776185481 @default.
- W2031552852 hasConceptScore W2031552852C2778960357 @default.
- W2031552852 hasConceptScore W2031552852C42972112 @default.
- W2031552852 hasConceptScore W2031552852C71924100 @default.
- W2031552852 hasConceptScore W2031552852C86803240 @default.
- W2031552852 hasFunder F4320306110 @default.
- W2031552852 hasFunder F4320306114 @default.
- W2031552852 hasFunder F4320320327 @default.
- W2031552852 hasIssue "20" @default.
- W2031552852 hasLocation W20315528521 @default.
- W2031552852 hasLocation W20315528522 @default.
- W2031552852 hasOpenAccess W2031552852 @default.
- W2031552852 hasPrimaryLocation W20315528521 @default.
- W2031552852 hasRelatedWork W1848516313 @default.
- W2031552852 hasRelatedWork W1933588764 @default.
- W2031552852 hasRelatedWork W1968853355 @default.
- W2031552852 hasRelatedWork W2020403813 @default.
- W2031552852 hasRelatedWork W2057745002 @default.
- W2031552852 hasRelatedWork W2082080978 @default.
- W2031552852 hasRelatedWork W2097160916 @default.
- W2031552852 hasRelatedWork W2150845218 @default.
- W2031552852 hasRelatedWork W2429243658 @default.
- W2031552852 hasRelatedWork W4318598245 @default.
- W2031552852 hasVolume "32" @default.
- W2031552852 isParatext "false" @default.
- W2031552852 isRetracted "false" @default.
- W2031552852 magId "2031552852" @default.
- W2031552852 workType "article" @default.