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• W2031562010 abstract "The current popularity of excimer laser refractive surgery suggests a need for continued research and refinements to further improve clinical outcomes. A fundamental limitation of current clinical systems is the lack of real-time feedback specifically addressing the laser-tissue interactions as directly related to laser ablation rates. This paper reports data to assess the feasibility of a novel approach that holds promise as a real-time feedback scheme based on comparison of the incident and reflected laser pulse waveforms, as quantified using a cross-correlation algorithm. The approach is evaluated for ablation of bovine cornea over a range of clinically relevant laser fluences. A linear relationship was observed between several cross-correlation metrics and the directly measured corneal ablation rate, yielding an average RMS predictive error of 3.9% using a 25-shot average reflected waveform. Assessment of the cross-correlation approach for single-shot ablation data revealed a brief transient corresponding to the first few laser pulses, which is attributed to a slight hydration gradient near the surface of the de-epithelialized cornea. Clinical refractive data are necessary to assess the precision of this approach for actual refractive surgery." @default.
• W2031562010 created "2016-06-24" @default.
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• W2031562010 date "2011-02-17" @default.
• W2031562010 modified "2023-10-14" @default.
• W2031562010 title "Real-time measurement of ArF excimer laser corneal tissue ablation rates using cross-correlation of laser waveforms" @default.
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• W2031562010 doi "https://doi.org/10.1364/oe.19.004231" @default.
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