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• W2031647527 abstract "To assess the incidence and impact on treatment and prognosis of occult lymph node metastasis in laryngeal cancer.A retrospective study was performed on 164 patients treated for laryngeal cancer, initially classified as N0, with cervical lymph node dissection.Occult metastases were found in 41 neck specimens (12.5%) from 32 patients (19.5%). Involvement per neck level was: 7% level IIa, 2.4% IIb, 4.2% III and 2.7% IV. Lymph node involvement was significantly increased in case of T3T4 tumor or invasion of the pre-epiglottic space or cartilage. Survival was significantly influenced by pN status (pN- = 12 years, vs pN+ = 9 years; P = 0.006).Level IIb or IV involvement is rare. Superselective neck dissection (IIa, III) seems to be indicated in T1T2 N0 tumor. In case of advanced tumor or pre-epiglottic space or cartilage invasion, functional neck dissection is mandatory." @default.
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• W2031647527 date "2010-11-01" @default.
• W2031647527 modified "2023-09-27" @default.
• W2031647527 title "Occult lymph node metastasis in laryngeal squamous cell carcinoma: Therapeutic and prognostic impact" @default.
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• W2031647527 doi "https://doi.org/10.1016/j.anorl.2010.07.011" @default.
• W2031647527 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21106463" @default.
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