Matches in SemOpenAlex for { <https://semopenalex.org/work/W2031648846> ?p ?o ?g. }
- W2031648846 endingPage "915" @default.
- W2031648846 startingPage "911" @default.
- W2031648846 abstract "Rats trained to self-administer cocaine (0.75 mg/kg/infusion) on an FR-5 schedule were treated with selective D1 or D2 antagonists. A69045, a D1 antagonist with no appreciable affinity for 5-HT receptors increased cocaine self-administration to 147, 172 and 167% of baseline at doses of 2.5, 5.0 or 10.0 mumol/kg, SC respectively. SCH-23390 (0.007, 0.015 and 0.030 mumol/kg, SC) increased self-administration to 116, 147 and 165% of baseline, respectively. Both D1 antagonists decreased responding in some animals at the highest dose tested. The D2 antagonist YM-09151-2 showed a similar profile, increasing cocaine self-administration at 0.01 and 0.016 mumol/kg, SC and suppressing responding by most animals at the dose of 0.03 mumol/kg, SC. These data give further support to the hypothesis that both D1 and D2 receptors are involved in maintaining cocaine self-administration." @default.
- W2031648846 created "2016-06-24" @default.
- W2031648846 creator A5001203681 @default.
- W2031648846 creator A5024835501 @default.
- W2031648846 creator A5029035402 @default.
- W2031648846 creator A5055776003 @default.
- W2031648846 creator A5064588218 @default.
- W2031648846 creator A5083071334 @default.
- W2031648846 date "1991-08-01" @default.
- W2031648846 modified "2023-10-18" @default.
- W2031648846 title "Evidence for involvement of both D1 and D2 receptors in maintaining cocaine self-administration" @default.
- W2031648846 cites W1969401266 @default.
- W2031648846 cites W1970637305 @default.
- W2031648846 cites W1975614312 @default.
- W2031648846 cites W1976403478 @default.
- W2031648846 cites W1991886920 @default.
- W2031648846 cites W1996371316 @default.
- W2031648846 cites W2004094484 @default.
- W2031648846 cites W2005897842 @default.
- W2031648846 cites W2008443947 @default.
- W2031648846 cites W2009756490 @default.
- W2031648846 cites W2023770577 @default.
- W2031648846 cites W2025951831 @default.
- W2031648846 cites W2030905853 @default.
- W2031648846 cites W2041080698 @default.
- W2031648846 cites W2041103283 @default.
- W2031648846 cites W2042681378 @default.
- W2031648846 cites W2050333093 @default.
- W2031648846 cites W2051372822 @default.
- W2031648846 cites W2059698180 @default.
- W2031648846 cites W2060746641 @default.
- W2031648846 cites W2061161259 @default.
- W2031648846 cites W2062080834 @default.
- W2031648846 cites W2069639335 @default.
- W2031648846 cites W2080984727 @default.
- W2031648846 cites W2088889438 @default.
- W2031648846 cites W2137266338 @default.
- W2031648846 cites W2159899816 @default.
- W2031648846 cites W2170810822 @default.
- W2031648846 cites W2174764226 @default.
- W2031648846 doi "https://doi.org/10.1016/0091-3057(91)90052-4" @default.
- W2031648846 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1684870" @default.
- W2031648846 hasPublicationYear "1991" @default.
- W2031648846 type Work @default.
- W2031648846 sameAs 2031648846 @default.
- W2031648846 citedByCount "88" @default.
- W2031648846 countsByYear W20316488462013 @default.
- W2031648846 countsByYear W20316488462014 @default.
- W2031648846 countsByYear W20316488462016 @default.
- W2031648846 countsByYear W20316488462017 @default.
- W2031648846 countsByYear W20316488462018 @default.
- W2031648846 countsByYear W20316488462020 @default.
- W2031648846 countsByYear W20316488462022 @default.
- W2031648846 crossrefType "journal-article" @default.
- W2031648846 hasAuthorship W2031648846A5001203681 @default.
- W2031648846 hasAuthorship W2031648846A5024835501 @default.
- W2031648846 hasAuthorship W2031648846A5029035402 @default.
- W2031648846 hasAuthorship W2031648846A5055776003 @default.
- W2031648846 hasAuthorship W2031648846A5064588218 @default.
- W2031648846 hasAuthorship W2031648846A5083071334 @default.
- W2031648846 hasConcept C126322002 @default.
- W2031648846 hasConcept C134018914 @default.
- W2031648846 hasConcept C170493617 @default.
- W2031648846 hasConcept C185592680 @default.
- W2031648846 hasConcept C2776885963 @default.
- W2031648846 hasConcept C2778122271 @default.
- W2031648846 hasConcept C2778555786 @default.
- W2031648846 hasConcept C2779917531 @default.
- W2031648846 hasConcept C44208683 @default.
- W2031648846 hasConcept C71924100 @default.
- W2031648846 hasConcept C98274493 @default.
- W2031648846 hasConceptScore W2031648846C126322002 @default.
- W2031648846 hasConceptScore W2031648846C134018914 @default.
- W2031648846 hasConceptScore W2031648846C170493617 @default.
- W2031648846 hasConceptScore W2031648846C185592680 @default.
- W2031648846 hasConceptScore W2031648846C2776885963 @default.
- W2031648846 hasConceptScore W2031648846C2778122271 @default.
- W2031648846 hasConceptScore W2031648846C2778555786 @default.
- W2031648846 hasConceptScore W2031648846C2779917531 @default.
- W2031648846 hasConceptScore W2031648846C44208683 @default.
- W2031648846 hasConceptScore W2031648846C71924100 @default.
- W2031648846 hasConceptScore W2031648846C98274493 @default.
- W2031648846 hasIssue "4" @default.
- W2031648846 hasLocation W20316488461 @default.
- W2031648846 hasLocation W20316488462 @default.
- W2031648846 hasOpenAccess W2031648846 @default.
- W2031648846 hasPrimaryLocation W20316488461 @default.
- W2031648846 hasRelatedWork W1982436434 @default.
- W2031648846 hasRelatedWork W2005897842 @default.
- W2031648846 hasRelatedWork W2007401955 @default.
- W2031648846 hasRelatedWork W2018311905 @default.
- W2031648846 hasRelatedWork W2063619316 @default.
- W2031648846 hasRelatedWork W2082168682 @default.
- W2031648846 hasRelatedWork W2148336481 @default.
- W2031648846 hasRelatedWork W2316932124 @default.
- W2031648846 hasRelatedWork W2748952813 @default.
- W2031648846 hasRelatedWork W3168384535 @default.
- W2031648846 hasVolume "39" @default.