FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2031708209> ?p ?o ?g. }

• W2031708209 endingPage "403" @default.
• W2031708209 startingPage "392" @default.
• W2031708209 abstract "Complex formation between nitrosoglutathione (GSNO) and Zn(II), Cd(II), and Ni(II) ions was studied by potentiometry and spectroscopic techniques. GSNO forms simple ML and ML2 type complexes (L = GSNO) with these ions. The stability of GSNO in HEPES buffer solution, pH 7.4, increased in the presence of both Zn(II) and Cd(II), due to an indirect mechanism. A concentration-dependent destabilization of GSNO by Ni(II) ions was found to be linearly dependent on the NiL complex concentration. NiL forms ternary complexes readily. The NiLA- stoichiometry was found for l-His, and NiHLB3- and NiLB4- complexes were detected for GSSG as the second ligand. The formation of these complexes was found to inhibit GSNO decay, by limiting the concentration of the NiL complex. The mechanism of Ni(II)-assisted GSNO decomposition contains several steps, with a hypothetical ternary complex with GSH as a likely active form. These results provide experimental evidence for the stabilization of GSNO in solution by metal ions, which may provide an additional level of control and/or impairment of cellular redox signaling. The Ni(II)-dependent destabilization of GSNO may constitute a novel epigenetic mechanism in nickel carcinogenesis." @default.
• W2031708209 created "2016-06-24" @default.
• W2031708209 creator A5015241918 @default.
• W2031708209 creator A5040649064 @default.
• W2031708209 date "2004-02-07" @default.
• W2031708209 modified "2023-09-29" @default.
• W2031708209 title "Contrasting Effects of Metal Ions on <i>S</i>-Nitrosoglutathione, Related to Coordination Equilibria: GSNO Decomposition Assisted by Ni(II) vs Stability Increase in the Presence of Zn(II) and Cd(II)" @default.
• W2031708209 cites W1269597682 @default.
• W2031708209 cites W1550055479 @default.
• W2031708209 cites W1973133531 @default.
• W2031708209 cites W1999311892 @default.
• W2031708209 cites W2002777248 @default.
• W2031708209 cites W2005205544 @default.
• W2031708209 cites W2022752686 @default.
• W2031708209 cites W2023488694 @default.
• W2031708209 cites W2029665946 @default.
• W2031708209 cites W2030243907 @default.
• W2031708209 cites W2037574965 @default.
• W2031708209 cites W2041792400 @default.
• W2031708209 cites W2053785073 @default.
• W2031708209 cites W2055961900 @default.
• W2031708209 cites W2065133438 @default.
• W2031708209 cites W2068359393 @default.
• W2031708209 cites W2074066467 @default.
• W2031708209 cites W2075116582 @default.
• W2031708209 cites W2087992143 @default.
• W2031708209 doi "https://doi.org/10.1021/tx034194i" @default.
• W2031708209 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15025510" @default.
• W2031708209 hasPublicationYear "2004" @default.
• W2031708209 type Work @default.
• W2031708209 sameAs 2031708209 @default.
• W2031708209 citedByCount "15" @default.
• W2031708209 countsByYear W20317082092012 @default.
• W2031708209 countsByYear W20317082092014 @default.
• W2031708209 countsByYear W20317082092015 @default.
• W2031708209 countsByYear W20317082092019 @default.
• W2031708209 countsByYear W20317082092020 @default.
• W2031708209 crossrefType "journal-article" @default.
• W2031708209 hasAuthorship W2031708209A5015241918 @default.
• W2031708209 hasAuthorship W2031708209A5040649064 @default.
• W2031708209 hasConcept C116569031 @default.
• W2031708209 hasConcept C124681953 @default.
• W2031708209 hasConcept C144082473 @default.
• W2031708209 hasConcept C145148216 @default.
• W2031708209 hasConcept C147789679 @default.
• W2031708209 hasConcept C170493617 @default.
• W2031708209 hasConcept C178790620 @default.
• W2031708209 hasConcept C179104552 @default.
• W2031708209 hasConcept C181199279 @default.
• W2031708209 hasConcept C185592680 @default.
• W2031708209 hasConcept C199164860 @default.
• W2031708209 hasConcept C199360897 @default.
• W2031708209 hasConcept C2776015013 @default.
• W2031708209 hasConcept C41008148 @default.
• W2031708209 hasConcept C504270822 @default.
• W2031708209 hasConcept C538909803 @default.
• W2031708209 hasConcept C544153396 @default.
• W2031708209 hasConcept C55493867 @default.
• W2031708209 hasConcept C64452783 @default.
• W2031708209 hasConcept C86756495 @default.
• W2031708209 hasConceptScore W2031708209C116569031 @default.
• W2031708209 hasConceptScore W2031708209C124681953 @default.
• W2031708209 hasConceptScore W2031708209C144082473 @default.
• W2031708209 hasConceptScore W2031708209C145148216 @default.
• W2031708209 hasConceptScore W2031708209C147789679 @default.
• W2031708209 hasConceptScore W2031708209C170493617 @default.
• W2031708209 hasConceptScore W2031708209C178790620 @default.
• W2031708209 hasConceptScore W2031708209C179104552 @default.
• W2031708209 hasConceptScore W2031708209C181199279 @default.
• W2031708209 hasConceptScore W2031708209C185592680 @default.
• W2031708209 hasConceptScore W2031708209C199164860 @default.
• W2031708209 hasConceptScore W2031708209C199360897 @default.
• W2031708209 hasConceptScore W2031708209C2776015013 @default.
• W2031708209 hasConceptScore W2031708209C41008148 @default.
• W2031708209 hasConceptScore W2031708209C504270822 @default.
• W2031708209 hasConceptScore W2031708209C538909803 @default.
• W2031708209 hasConceptScore W2031708209C544153396 @default.
• W2031708209 hasConceptScore W2031708209C55493867 @default.
• W2031708209 hasConceptScore W2031708209C64452783 @default.
• W2031708209 hasConceptScore W2031708209C86756495 @default.
• W2031708209 hasIssue "3" @default.
• W2031708209 hasLocation W20317082091 @default.
• W2031708209 hasLocation W20317082092 @default.
• W2031708209 hasOpenAccess W2031708209 @default.
• W2031708209 hasPrimaryLocation W20317082091 @default.
• W2031708209 hasRelatedWork W1966756687 @default.
• W2031708209 hasRelatedWork W1975039292 @default.
• W2031708209 hasRelatedWork W2031881328 @default.
• W2031708209 hasRelatedWork W2053775851 @default.
• W2031708209 hasRelatedWork W2060747192 @default.
• W2031708209 hasRelatedWork W2084265096 @default.
• W2031708209 hasRelatedWork W3210691475 @default.
• W2031708209 hasRelatedWork W4229375646 @default.
• W2031708209 hasRelatedWork W4382140333 @default.
• W2031708209 hasRelatedWork W2089023618 @default.
• W2031708209 hasVolume "17" @default.
• W2031708209 isParatext "false" @default.
• W2031708209 isRetracted "false" @default.

• next