FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2031742059> ?p ?o ?g. }

• W2031742059 endingPage "939" @default.
• W2031742059 startingPage "933" @default.
• W2031742059 abstract "We conducted a clinical trial of rhesus rotavirus vaccine MMU-18006 (RRV, serotype 3) to assess the immunogenicity, transmissibility and booster effect of this vaccine in a welfare nursery in Sapporo, from September 1986 to October 1988. After the trial, in March 1989, an outbreak of gastroenteritis due to a wild strain of serotype 1 rotavirus (RV-1) occurred in the study population. Infants were divided into three groups based on vaccination history: five booster vaccinees, 18 one-dose vaccinees and 18 control infants who did not receive vaccine. There was a significant relationship between asymptomatic infection and higher levels of preoutbreak antibody titres against KU (serotype 1) but not RRV. Significant protection from rotavirus illness was observed both in the booster vaccine group and in the one-dose vaccine group but not the control group. Rotavirus-specific serum IgA immune response was considered to be one of the indicators of recent rotavirus infection, and did not correlate with resistance to rotavirus illness. Our results revealed that protection from rotavirus illness was serotype-specific and that previous rotavirus infection, including vaccination, was important to induce the heterotypic immune response, and that ageing or booster inoculation of RRV might play a role in the protection against serotype 1 rotavirus infection. From our findings, a booster administration was thought to be important to induce effective heterotypic immunity and should be included in a future rotavirus vaccine trial to obtain sufficient protection against four major serotypes of rotavirus." @default.
• W2031742059 created "2016-06-24" @default.
• W2031742059 creator A5020750724 @default.
• W2031742059 creator A5021138656 @default.
• W2031742059 creator A5035973083 @default.
• W2031742059 creator A5041878990 @default.
• W2031742059 creator A5057783683 @default.
• W2031742059 date "1994-01-01" @default.
• W2031742059 modified "2023-09-26" @default.
• W2031742059 title "Efficacy of rhesus rotavirus vaccine MMU-18006 against gastroenteritis due to serotype 1 rotavirus" @default.
• W2031742059 cites W1492320425 @default.
• W2031742059 cites W1542651923 @default.
• W2031742059 cites W1569200484 @default.
• W2031742059 cites W1642524402 @default.
• W2031742059 cites W1761322105 @default.
• W2031742059 cites W1783789378 @default.
• W2031742059 cites W1940447935 @default.
• W2031742059 cites W1977428260 @default.
• W2031742059 cites W1981780275 @default.
• W2031742059 cites W1987660880 @default.
• W2031742059 cites W2006502876 @default.
• W2031742059 cites W2040659583 @default.
• W2031742059 cites W2045888972 @default.
• W2031742059 cites W2065920259 @default.
• W2031742059 cites W2077036786 @default.
• W2031742059 cites W2092273797 @default.
• W2031742059 cites W2101175832 @default.
• W2031742059 cites W2104472592 @default.
• W2031742059 cites W2123206247 @default.
• W2031742059 cites W2127376324 @default.
• W2031742059 cites W2127447898 @default.
• W2031742059 cites W2141691810 @default.
• W2031742059 cites W2143485489 @default.
• W2031742059 cites W2149015121 @default.
• W2031742059 cites W2153949562 @default.
• W2031742059 cites W2158450124 @default.
• W2031742059 cites W2321194422 @default.
• W2031742059 cites W2003050383 @default.
• W2031742059 doi "https://doi.org/10.1016/0264-410x(94)90037-x" @default.
• W2031742059 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7975835" @default.
• W2031742059 hasPublicationYear "1994" @default.
• W2031742059 type Work @default.
• W2031742059 sameAs 2031742059 @default.
• W2031742059 citedByCount "14" @default.
• W2031742059 crossrefType "journal-article" @default.
• W2031742059 hasAuthorship W2031742059A5020750724 @default.
• W2031742059 hasAuthorship W2031742059A5021138656 @default.
• W2031742059 hasAuthorship W2031742059A5035973083 @default.
• W2031742059 hasAuthorship W2031742059A5041878990 @default.
• W2031742059 hasAuthorship W2031742059A5057783683 @default.
• W2031742059 hasConcept C10389963 @default.
• W2031742059 hasConcept C159047783 @default.
• W2031742059 hasConcept C203014093 @default.
• W2031742059 hasConcept C22070199 @default.
• W2031742059 hasConcept C2522874641 @default.
• W2031742059 hasConcept C2777227250 @default.
• W2031742059 hasConcept C2779416561 @default.
• W2031742059 hasConcept C2780441014 @default.
• W2031742059 hasConcept C2780868878 @default.
• W2031742059 hasConcept C2781367151 @default.
• W2031742059 hasConcept C2908647359 @default.
• W2031742059 hasConcept C71924100 @default.
• W2031742059 hasConcept C86803240 @default.
• W2031742059 hasConcept C8891405 @default.
• W2031742059 hasConcept C99454951 @default.
• W2031742059 hasConceptScore W2031742059C10389963 @default.
• W2031742059 hasConceptScore W2031742059C159047783 @default.
• W2031742059 hasConceptScore W2031742059C203014093 @default.
• W2031742059 hasConceptScore W2031742059C22070199 @default.
• W2031742059 hasConceptScore W2031742059C2522874641 @default.
• W2031742059 hasConceptScore W2031742059C2777227250 @default.
• W2031742059 hasConceptScore W2031742059C2779416561 @default.
• W2031742059 hasConceptScore W2031742059C2780441014 @default.
• W2031742059 hasConceptScore W2031742059C2780868878 @default.
• W2031742059 hasConceptScore W2031742059C2781367151 @default.
• W2031742059 hasConceptScore W2031742059C2908647359 @default.
• W2031742059 hasConceptScore W2031742059C71924100 @default.
• W2031742059 hasConceptScore W2031742059C86803240 @default.
• W2031742059 hasConceptScore W2031742059C8891405 @default.
• W2031742059 hasConceptScore W2031742059C99454951 @default.
• W2031742059 hasIssue "10" @default.
• W2031742059 hasLocation W20317420591 @default.
• W2031742059 hasLocation W20317420592 @default.
• W2031742059 hasOpenAccess W2031742059 @default.
• W2031742059 hasPrimaryLocation W20317420591 @default.
• W2031742059 hasRelatedWork W162571944 @default.
• W2031742059 hasRelatedWork W1974337650 @default.
• W2031742059 hasRelatedWork W2017408238 @default.
• W2031742059 hasRelatedWork W2020612572 @default.
• W2031742059 hasRelatedWork W2087032545 @default.
• W2031742059 hasRelatedWork W2092273797 @default.
• W2031742059 hasRelatedWork W2123206247 @default.
• W2031742059 hasRelatedWork W2126402298 @default.
• W2031742059 hasRelatedWork W2161559850 @default.
• W2031742059 hasRelatedWork W2465253705 @default.
• W2031742059 hasVolume "12" @default.
• W2031742059 isParatext "false" @default.
• W2031742059 isRetracted "false" @default.

• next