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- W2031742834 abstract "Disorders of magnesium homeostasis are very common in dialysis patients but have received scant attention. In this review, we address measurement of plasma magnesium, magnesium balance and the factors that affect magnesium flux during dialysis, the prevalence of hypo- and hypermagnesemia in dialysis patients, and the potential clinical significance of hypo- and hypermagnesemia in dialysis patients. Many factors can affect plasma magnesium concentration, including diet, nutritional status (including plasma albumin level), medications (such as proton pump inhibitors), and dialysis prescription. Further interventional studies to determine the effect of normalization of plasma magnesium concentration on clinical outcomes are needed. At the present time, we recommend that predialysis plasma magnesium be measured on a regular basis, with the dialysate magnesium concentration adjusted to maintain plasma magnesium concentration within the normal range. Disorders of magnesium homeostasis are very common in dialysis patients but have received scant attention. In this review, we address measurement of plasma magnesium, magnesium balance and the factors that affect magnesium flux during dialysis, the prevalence of hypo- and hypermagnesemia in dialysis patients, and the potential clinical significance of hypo- and hypermagnesemia in dialysis patients. Many factors can affect plasma magnesium concentration, including diet, nutritional status (including plasma albumin level), medications (such as proton pump inhibitors), and dialysis prescription. Further interventional studies to determine the effect of normalization of plasma magnesium concentration on clinical outcomes are needed. At the present time, we recommend that predialysis plasma magnesium be measured on a regular basis, with the dialysate magnesium concentration adjusted to maintain plasma magnesium concentration within the normal range. Optimal Plasma and Dialysate Magnesium Concentrations in Hemodialysis Patients: The Unsettled IssuesAmerican Journal of Kidney DiseasesVol. 67Issue 2PreviewWe read with interest the review article by Alhosaini and Leehey1 on magnesium balance, flux during hemodialysis (HD), and the clinical significance of magnesium disorders in patients treated by HD. The authors reasonably concluded that predialysis magnesium should be regularly measured and dialysate magnesium concentration should be adjusted to maintain plasma magnesium concentrations within the normal range. Full-Text PDF" @default.
- W2031742834 created "2016-06-24" @default.
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- W2031742834 date "2015-09-01" @default.
- W2031742834 modified "2023-09-30" @default.
- W2031742834 title "Magnesium and Dialysis: The Neglected Cation" @default.
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- W2031742834 doi "https://doi.org/10.1053/j.ajkd.2015.01.029" @default.
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