FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2031743190> ?p ?o ?g. }

• W2031743190 endingPage "B250" @default.
• W2031743190 startingPage "B243" @default.
• W2031743190 abstract "Super-paramagnetic iron oxide nanoparticles (SPIONs) are recognized as powerful biocompatible materials for use in various biomedical applications, such as drug delivery, magnetic-resonance imaging, cell/protein separation, hyperthermia and transfection. This study investigates the impact of high concentrations of SPIONs on cytotoxicity and cell-cycle effects. The interactions of surface-saturated (via interactions with cell medium) bare SPIONs and those coated with poly(vinyl alcohol) (PVA) with adhesive mouse fibroblast cells (L929) are investigated using an MTT assay. The two SPION formulations are synthesized using a co-precipitation method. The bare and coated magnetic nanoparticles with passivated surfaces both result in changes in cell morphology, possibly due to clustering through their magnetostatic effect. At concentrations ranging up to 80 × 10−3 M, cells exposed to the PVA-coated nanoparticles demonstrate high cell viability without necrosis and apoptosis. In contrast, significant apoptosis is observed in cells exposed to bare SPIONs at a concentration of 80 × 10−3 M. Nanoparticle exposure (20–80 × 10−3 M) leads to variations in both apoptosis and cell cycle, possibly due to irreversible DNA damage and repair of oxidative DNA lesions, respectively. Additionally, the formation of vacuoles within the cells and granular cells indicates autophagy cell death rather than either apoptosis or necrosis." @default.
• W2031743190 created "2016-06-24" @default.
• W2031743190 creator A5007285706 @default.
• W2031743190 creator A5010216492 @default.
• W2031743190 creator A5027550212 @default.
• W2031743190 creator A5071896350 @default.
• W2031743190 creator A5081564266 @default.
• W2031743190 creator A5086758342 @default.
• W2031743190 creator A5088377096 @default.
• W2031743190 date "2009-12-01" @default.
• W2031743190 modified "2023-10-16" @default.
• W2031743190 title "Cytotoxicity and Cell Cycle Effects of Bare and Poly(vinyl alcohol)-Coated Iron Oxide Nanoparticles in Mouse Fibroblasts" @default.
• W2031743190 cites W1966476051 @default.
• W2031743190 cites W1973626807 @default.
• W2031743190 cites W1990586782 @default.
• W2031743190 cites W1991659188 @default.
• W2031743190 cites W1996366132 @default.
• W2031743190 cites W2001154198 @default.
• W2031743190 cites W2006543510 @default.
• W2031743190 cites W2007633508 @default.
• W2031743190 cites W2028315723 @default.
• W2031743190 cites W2039506150 @default.
• W2031743190 cites W2042766516 @default.
• W2031743190 cites W2046428284 @default.
• W2031743190 cites W2049869110 @default.
• W2031743190 cites W2051183893 @default.
• W2031743190 cites W2053992046 @default.
• W2031743190 cites W2070550561 @default.
• W2031743190 cites W2084132208 @default.
• W2031743190 cites W2094262202 @default.
• W2031743190 cites W2097830080 @default.
• W2031743190 cites W2111124655 @default.
• W2031743190 cites W2127397597 @default.
• W2031743190 cites W2134457997 @default.
• W2031743190 cites W2153818530 @default.
• W2031743190 cites W4236123490 @default.
• W2031743190 doi "https://doi.org/10.1002/adem.200990035" @default.
• W2031743190 hasPublicationYear "2009" @default.
• W2031743190 type Work @default.
• W2031743190 sameAs 2031743190 @default.
• W2031743190 citedByCount "55" @default.
• W2031743190 countsByYear W20317431902012 @default.
• W2031743190 countsByYear W20317431902013 @default.
• W2031743190 countsByYear W20317431902014 @default.
• W2031743190 countsByYear W20317431902015 @default.
• W2031743190 countsByYear W20317431902016 @default.
• W2031743190 countsByYear W20317431902017 @default.
• W2031743190 countsByYear W20317431902018 @default.
• W2031743190 countsByYear W20317431902019 @default.
• W2031743190 countsByYear W20317431902020 @default.
• W2031743190 countsByYear W20317431902021 @default.
• W2031743190 countsByYear W20317431902022 @default.
• W2031743190 countsByYear W20317431902023 @default.
• W2031743190 crossrefType "journal-article" @default.
• W2031743190 hasAuthorship W2031743190A5007285706 @default.
• W2031743190 hasAuthorship W2031743190A5010216492 @default.
• W2031743190 hasAuthorship W2031743190A5027550212 @default.
• W2031743190 hasAuthorship W2031743190A5071896350 @default.
• W2031743190 hasAuthorship W2031743190A5081564266 @default.
• W2031743190 hasAuthorship W2031743190A5086758342 @default.
• W2031743190 hasAuthorship W2031743190A5088377096 @default.
• W2031743190 hasConcept C109316439 @default.
• W2031743190 hasConcept C12554922 @default.
• W2031743190 hasConcept C1491633281 @default.
• W2031743190 hasConcept C155672457 @default.
• W2031743190 hasConcept C171250308 @default.
• W2031743190 hasConcept C185592680 @default.
• W2031743190 hasConcept C190283241 @default.
• W2031743190 hasConcept C192562407 @default.
• W2031743190 hasConcept C202751555 @default.
• W2031743190 hasConcept C2780381497 @default.
• W2031743190 hasConcept C2780783641 @default.
• W2031743190 hasConcept C29537977 @default.
• W2031743190 hasConcept C53227056 @default.
• W2031743190 hasConcept C55493867 @default.
• W2031743190 hasConcept C86803240 @default.
• W2031743190 hasConceptScore W2031743190C109316439 @default.
• W2031743190 hasConceptScore W2031743190C12554922 @default.
• W2031743190 hasConceptScore W2031743190C1491633281 @default.
• W2031743190 hasConceptScore W2031743190C155672457 @default.
• W2031743190 hasConceptScore W2031743190C171250308 @default.
• W2031743190 hasConceptScore W2031743190C185592680 @default.
• W2031743190 hasConceptScore W2031743190C190283241 @default.
• W2031743190 hasConceptScore W2031743190C192562407 @default.
• W2031743190 hasConceptScore W2031743190C202751555 @default.
• W2031743190 hasConceptScore W2031743190C2780381497 @default.
• W2031743190 hasConceptScore W2031743190C2780783641 @default.
• W2031743190 hasConceptScore W2031743190C29537977 @default.
• W2031743190 hasConceptScore W2031743190C53227056 @default.
• W2031743190 hasConceptScore W2031743190C55493867 @default.
• W2031743190 hasConceptScore W2031743190C86803240 @default.
• W2031743190 hasIssue "12" @default.
• W2031743190 hasLocation W20317431901 @default.
• W2031743190 hasOpenAccess W2031743190 @default.
• W2031743190 hasPrimaryLocation W20317431901 @default.
• W2031743190 hasRelatedWork W1191950147 @default.
• W2031743190 hasRelatedWork W1933341309 @default.
• W2031743190 hasRelatedWork W1993427159 @default.

• next