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• W2031767508 abstract "Obesity has reached pandemic proportions and is associated with serious cardiometabolic sequelae including insulin resistance, diabetes, dyslipidemia, hypertension, and cardiovascular disease, where adipose tissue-secreted cytokines, that is, adipokines, have been implicated in these processes. Omentin is a novel adipokine preferentially produced by visceral adipose tissue with insulin-sensitizing effects, where circulating levels are decreased in insulin-resistant states, for example, obesity and diabetes. With respect to vascular biology, omentin causes vasodilatation of blood vessels and attenuates C-reactive protein-induced angiogenesis potentially via the nuclear factor B signaling pathway, a potent proinflammatory signaling pathway. Thus, omentin may have beneficial effects on the metabolic syndrome and could potentially be used as a biologic marker and/or pharmacologic agent in this respect." @default.
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• W2031767508 date "2010-07-01" @default.
• W2031767508 modified "2023-10-05" @default.
• W2031767508 title "Omentin: A Novel Link Between Inflammation, Diabesity, and Cardiovascular Disease" @default.
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• W2031767508 doi "https://doi.org/10.1016/j.tcm.2010.12.002" @default.
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