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• W2031787885 endingPage "8370" @default.
• W2031787885 startingPage "8366" @default.
• W2031787885 abstract "Immediately after focal retinal lesions, receptive fields (RFs) in primary visual cortex expand considerably, even when the retinal damage is limited to the photoreceptor layer. The time course of these changes suggests that mere lack of stimulation in the vicinity of the RF accompanied by stimulation in the surrounding region causes the RF expansion. While recording from single cells in cat area 17, we simulated this pattern of stimulation with a pattern of moving lines in the visual field, masking out an area covering the RF of the recorded cell, thereby producing an artificial scotoma. Over approximately 10 min this masking resulted in a 5-fold average expansion in RF area. Stimulating the RF center caused the field to collapse in size, returning to near its original extent; reconditioning with the masked stimulus led to RF reexpansion. Stimulation in the surrounding region was required for the RF expansion to occur--little expansion was seen during exposure to a blank screen. We propose that the expansion may account for visual illusions, such as perceptual fill-in of stabilized images and illusory contours and may constitute the prodrome of altered cortical topography after retinal lesions. These findings support the idea that even in adult animals RFs are dynamic, capable of being altered by the sensory context." @default.
• W2031787885 created "2016-06-24" @default.
• W2031787885 creator A5046159550 @default.
• W2031787885 creator A5081633208 @default.
• W2031787885 date "1992-09-01" @default.
• W2031787885 modified "2023-09-23" @default.
• W2031787885 title "Dynamic changes in receptive-field size in cat primary visual cortex." @default.
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• W2031787885 doi "https://doi.org/10.1073/pnas.89.17.8366" @default.
• W2031787885 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/49919" @default.
• W2031787885 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1518870" @default.
• W2031787885 hasPublicationYear "1992" @default.
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