FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2031802960> ?p ?o ?g. }

• W2031802960 endingPage "182" @default.
• W2031802960 startingPage "172" @default.
• W2031802960 abstract "An increasing number of data involve immunoreceptors in brain development, synaptic plasticity and behavior. However it has yet to be determined whether these proteins in fact transmit an immunoreceptor-like signal in non-hematopoietic neuronal cells. The recruitment and activation of the Syk family tyrosine kinases, Syk and ZAP-70, being a critical step in this process, we conducted a thorough analysis of Syk/ZAP-70 expression pattern in nervous tissues. Syk/ZAP-70 is present in neurons of different structures including the cerebellum, the hippocampus, the visual system and the olfactory system. During the olfactory system ontogeny the protein is detected from the 16th embryonic day and persists in adulthood. Importantly, Syk was phosphorylated on tyrosine residues representative of an active form of the kinase in specialized neuronal subpopulations comprising rostral migratory stream neuronal progenitor cells, hippocampal pyramidal cells, retinal ganglion cells and cerebellar granular cells. Phospho-Syk staining was also observed in synapse-rich regions such as the olfactory bulb glomeruli and the retina inner plexiform layer. Furthermore, our work on cultured primary hippoccampal neurons indicates that as for hematopoietic cells, Syk phosphorylation is readily induced upon pervanadate treatment. Therefore, Syk appears to be a serious candidate in connecting immunoreceptors to downstream adaptor/effector molecules in neurons." @default.
• W2031802960 created "2016-06-24" @default.
• W2031802960 creator A5000142892 @default.
• W2031802960 creator A5013922203 @default.
• W2031802960 creator A5020818599 @default.
• W2031802960 creator A5041876253 @default.
• W2031802960 creator A5043145257 @default.
• W2031802960 creator A5061141183 @default.
• W2031802960 creator A5069221051 @default.
• W2031802960 creator A5079278808 @default.
• W2031802960 creator A5086042423 @default.
• W2031802960 creator A5086293771 @default.
• W2031802960 date "2011-06-01" @default.
• W2031802960 modified "2023-10-15" @default.
• W2031802960 title "Syk kinase is phosphorylated in specific areas of the developing nervous system" @default.
• W2031802960 cites W1495813857 @default.
• W2031802960 cites W1526397263 @default.
• W2031802960 cites W1659855560 @default.
• W2031802960 cites W1667965282 @default.
• W2031802960 cites W1895213472 @default.
• W2031802960 cites W1964910777 @default.
• W2031802960 cites W1968332969 @default.
• W2031802960 cites W1980385765 @default.
• W2031802960 cites W1991325120 @default.
• W2031802960 cites W2003502718 @default.
• W2031802960 cites W2004333326 @default.
• W2031802960 cites W2004644593 @default.
• W2031802960 cites W2005857763 @default.
• W2031802960 cites W2018843440 @default.
• W2031802960 cites W2022418824 @default.
• W2031802960 cites W2023378097 @default.
• W2031802960 cites W2030161749 @default.
• W2031802960 cites W2041726757 @default.
• W2031802960 cites W2042759576 @default.
• W2031802960 cites W2053901332 @default.
• W2031802960 cites W2055144719 @default.
• W2031802960 cites W2065427561 @default.
• W2031802960 cites W2083443411 @default.
• W2031802960 cites W2086702469 @default.
• W2031802960 cites W2088057180 @default.
• W2031802960 cites W2089783130 @default.
• W2031802960 cites W2105562449 @default.
• W2031802960 cites W2113704934 @default.
• W2031802960 cites W2115453329 @default.
• W2031802960 cites W2119270366 @default.
• W2031802960 cites W2119790860 @default.
• W2031802960 cites W2125258541 @default.
• W2031802960 cites W2125284377 @default.
• W2031802960 cites W2149418167 @default.
• W2031802960 cites W2150026822 @default.
• W2031802960 cites W2150074283 @default.
• W2031802960 cites W2165686609 @default.
• W2031802960 cites W2167022467 @default.
• W2031802960 cites W2169288421 @default.
• W2031802960 doi "https://doi.org/10.1016/j.neures.2011.02.008" @default.
• W2031802960 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21354221" @default.
• W2031802960 hasPublicationYear "2011" @default.
• W2031802960 type Work @default.
• W2031802960 sameAs 2031802960 @default.
• W2031802960 citedByCount "8" @default.
• W2031802960 countsByYear W20318029602012 @default.
• W2031802960 countsByYear W20318029602016 @default.
• W2031802960 countsByYear W20318029602017 @default.
• W2031802960 countsByYear W20318029602019 @default.
• W2031802960 crossrefType "journal-article" @default.
• W2031802960 hasAuthorship W2031802960A5000142892 @default.
• W2031802960 hasAuthorship W2031802960A5013922203 @default.
• W2031802960 hasAuthorship W2031802960A5020818599 @default.
• W2031802960 hasAuthorship W2031802960A5041876253 @default.
• W2031802960 hasAuthorship W2031802960A5043145257 @default.
• W2031802960 hasAuthorship W2031802960A5061141183 @default.
• W2031802960 hasAuthorship W2031802960A5069221051 @default.
• W2031802960 hasAuthorship W2031802960A5079278808 @default.
• W2031802960 hasAuthorship W2031802960A5086042423 @default.
• W2031802960 hasAuthorship W2031802960A5086293771 @default.
• W2031802960 hasConcept C11960822 @default.
• W2031802960 hasConcept C169760540 @default.
• W2031802960 hasConcept C2777553839 @default.
• W2031802960 hasConcept C2779652256 @default.
• W2031802960 hasConcept C2780496858 @default.
• W2031802960 hasConcept C35174551 @default.
• W2031802960 hasConcept C42362537 @default.
• W2031802960 hasConcept C529278444 @default.
• W2031802960 hasConcept C545706735 @default.
• W2031802960 hasConcept C62478195 @default.
• W2031802960 hasConcept C86803240 @default.
• W2031802960 hasConcept C95444343 @default.
• W2031802960 hasConceptScore W2031802960C11960822 @default.
• W2031802960 hasConceptScore W2031802960C169760540 @default.
• W2031802960 hasConceptScore W2031802960C2777553839 @default.
• W2031802960 hasConceptScore W2031802960C2779652256 @default.
• W2031802960 hasConceptScore W2031802960C2780496858 @default.
• W2031802960 hasConceptScore W2031802960C35174551 @default.
• W2031802960 hasConceptScore W2031802960C42362537 @default.
• W2031802960 hasConceptScore W2031802960C529278444 @default.
• W2031802960 hasConceptScore W2031802960C545706735 @default.
• W2031802960 hasConceptScore W2031802960C62478195 @default.
• W2031802960 hasConceptScore W2031802960C86803240 @default.

• next