Matches in SemOpenAlex for { <https://semopenalex.org/work/W2031808761> ?p ?o ?g. }
- W2031808761 endingPage "194" @default.
- W2031808761 startingPage "185" @default.
- W2031808761 abstract "This review examines the multiple levels of pre-existing immunity in the upper and lower female reproductive tract. In addition, we highlight the need for further research of innate and adaptive immune protection of mucosal surfaces in the female reproductive tract. Innate mechanisms include the mucus lining, a tight epithelial barrier and the secretion of antimicrobial peptides and cytokines by epithelial and innate immune cells. Stimulation of the innate immune system also serves to bridge the adaptive arm resulting in the generation of pathogen-specific humoral and cell-mediated immunity. Less understood are the multiple components that act in a coordinated way to provide a network of ongoing protection. Innate and adaptive immunity in the human female reproductive tract are influenced by the stage of menstrual cycle and are directly regulated by the sex steroid hormones, progesterone and estradiol. Furthermore, the effect of hormones on immunity is mediated both directly on immune and epithelial cells and indirectly by stimulating growth factor secretion from stromal cells. The goal of this review is to focus on the diverse aspects of the innate and adaptive immune systems that contribute to a unique network of protection throughout the female reproductive tract." @default.
- W2031808761 created "2016-06-24" @default.
- W2031808761 creator A5003141492 @default.
- W2031808761 creator A5017248220 @default.
- W2031808761 creator A5051919392 @default.
- W2031808761 creator A5075967066 @default.
- W2031808761 date "2011-03-01" @default.
- W2031808761 modified "2023-10-17" @default.
- W2031808761 title "Innate and adaptive immunity at mucosal surfaces of the female reproductive tract: stratification and integration of immune protection against the transmission of sexually transmitted infections" @default.
- W2031808761 cites W1548322053 @default.
- W2031808761 cites W1575669396 @default.
- W2031808761 cites W1580530110 @default.
- W2031808761 cites W1628777611 @default.
- W2031808761 cites W1835714742 @default.
- W2031808761 cites W1848970261 @default.
- W2031808761 cites W1945859829 @default.
- W2031808761 cites W1984200532 @default.
- W2031808761 cites W1990798154 @default.
- W2031808761 cites W1994710883 @default.
- W2031808761 cites W1994810578 @default.
- W2031808761 cites W2004977770 @default.
- W2031808761 cites W2005445619 @default.
- W2031808761 cites W2006266678 @default.
- W2031808761 cites W2008002949 @default.
- W2031808761 cites W2009830841 @default.
- W2031808761 cites W2017410453 @default.
- W2031808761 cites W2018152487 @default.
- W2031808761 cites W2020173029 @default.
- W2031808761 cites W2021686444 @default.
- W2031808761 cites W2021750859 @default.
- W2031808761 cites W2023674625 @default.
- W2031808761 cites W2024979614 @default.
- W2031808761 cites W2025837117 @default.
- W2031808761 cites W2026269930 @default.
- W2031808761 cites W2029383014 @default.
- W2031808761 cites W2035200272 @default.
- W2031808761 cites W2038904717 @default.
- W2031808761 cites W2043104844 @default.
- W2031808761 cites W2046142660 @default.
- W2031808761 cites W2048254575 @default.
- W2031808761 cites W2050211620 @default.
- W2031808761 cites W2052160940 @default.
- W2031808761 cites W2055177612 @default.
- W2031808761 cites W2057198053 @default.
- W2031808761 cites W2057676166 @default.
- W2031808761 cites W2059937568 @default.
- W2031808761 cites W2063698734 @default.
- W2031808761 cites W2065472139 @default.
- W2031808761 cites W2065545997 @default.
- W2031808761 cites W2066402568 @default.
- W2031808761 cites W2075201634 @default.
- W2031808761 cites W2076744423 @default.
- W2031808761 cites W2078489697 @default.
- W2031808761 cites W2084426473 @default.
- W2031808761 cites W2088968901 @default.
- W2031808761 cites W2093135399 @default.
- W2031808761 cites W2095747840 @default.
- W2031808761 cites W2099851196 @default.
- W2031808761 cites W2103658596 @default.
- W2031808761 cites W2105565836 @default.
- W2031808761 cites W2106238870 @default.
- W2031808761 cites W2107339432 @default.
- W2031808761 cites W2110501239 @default.
- W2031808761 cites W2113276215 @default.
- W2031808761 cites W2113463914 @default.
- W2031808761 cites W2113857827 @default.
- W2031808761 cites W2119991902 @default.
- W2031808761 cites W2126210741 @default.
- W2031808761 cites W2127136379 @default.
- W2031808761 cites W2127190620 @default.
- W2031808761 cites W2128597422 @default.
- W2031808761 cites W2132622748 @default.
- W2031808761 cites W2136327125 @default.
- W2031808761 cites W2136608299 @default.
- W2031808761 cites W2139561917 @default.
- W2031808761 cites W2143935360 @default.
- W2031808761 cites W2149317992 @default.
- W2031808761 cites W2152924923 @default.
- W2031808761 cites W2155074182 @default.
- W2031808761 cites W2158215737 @default.
- W2031808761 cites W2160892965 @default.
- W2031808761 cites W2161024777 @default.
- W2031808761 cites W2161960954 @default.
- W2031808761 cites W2164127681 @default.
- W2031808761 cites W2170665356 @default.
- W2031808761 cites W2339791846 @default.
- W2031808761 cites W2791218690 @default.
- W2031808761 cites W4256376274 @default.
- W2031808761 cites W49611453 @default.
- W2031808761 doi "https://doi.org/10.1016/j.jri.2011.01.005" @default.
- W2031808761 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3094911" @default.
- W2031808761 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21353708" @default.
- W2031808761 hasPublicationYear "2011" @default.
- W2031808761 type Work @default.
- W2031808761 sameAs 2031808761 @default.
- W2031808761 citedByCount "191" @default.
- W2031808761 countsByYear W20318087612012 @default.
- W2031808761 countsByYear W20318087612013 @default.