FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2031808788> ?p ?o ?g. }

• W2031808788 abstract "Abstract In a preceding paper (Schroder and Kaerner, 1972) a rolling circle mechanism has been described for the replication of bacteriophage φX174 replicative form. Replication involved nicking and elongation of the viral (positive) strand component of the RF molecule resulting in the displacement of a single-strand tail of increasing length. The synthesis of the new complementary (negative) strand on the single-strand tails appears to be initiated with considerable delay and converts the tail into double-stranded DNA. Before the new negative strand is completed the replicative intermediates split into (I) a complete RF molecule containing the “old” negative and the new positive strand, and (II) a linear, partially double-stranded “tail” consisting of the complete old positive strand and a fragment of the new negative strand. The present study is concerned with the fate during RF replication of these fragments of the rolling circles. Those RFII molecules containing the old negative strands appear to go into further replication rounds repeatedly. Some of the tails were found in the infected cells in their original linear form. “Gapped” RFII molecules, which have been described earlier by Schekman and co-workers (Schekman & Ray, 1971; Schekman et al. , 1971), are supposed to originate from the tails of rolling circle intermediates by circularization of their positive strand components. Evidence is provided by our experiments that even late during RF replication these gaps are present only in the negative strands of RFII. Appropriate chase experiments indicated that the tails finally are converted to RFI molecules. Progeny RFI molecules could not be observed to start new replication rounds under our conditions although we cannot exclude that this might happen to some minor extent. The results presented suggest that the master templates for RF replication are the first negative strands to be formed, rather than the parental positive strands." @default.
• W2031808788 created "2016-06-24" @default.
• W2031808788 creator A5028220132 @default.
• W2031808788 creator A5068364757 @default.
• W2031808788 creator A5070876441 @default.
• W2031808788 date "1973-10-01" @default.
• W2031808788 modified "2023-09-27" @default.
• W2031808788 title "A rolling circle model of the in vivo replication of bacteriophage φX174 replicative form DNA: Different fate of two types of progeny replicative form" @default.
• W2031808788 cites W1482745452 @default.
• W2031808788 cites W1500716268 @default.
• W2031808788 cites W1513815820 @default.
• W2031808788 cites W1517125516 @default.
• W2031808788 cites W1526053653 @default.
• W2031808788 cites W1531931727 @default.
• W2031808788 cites W1546758176 @default.
• W2031808788 cites W1549906129 @default.
• W2031808788 cites W1574122748 @default.
• W2031808788 cites W1580360342 @default.
• W2031808788 cites W1924651386 @default.
• W2031808788 cites W1978650322 @default.
• W2031808788 cites W1993507685 @default.
• W2031808788 cites W2012156321 @default.
• W2031808788 cites W2013007502 @default.
• W2031808788 cites W2018747901 @default.
• W2031808788 cites W2019602984 @default.
• W2031808788 cites W2050860000 @default.
• W2031808788 cites W2064092083 @default.
• W2031808788 cites W2083767310 @default.
• W2031808788 cites W2095335832 @default.
• W2031808788 cites W2244605364 @default.
• W2031808788 cites W2325115828 @default.
• W2031808788 doi "https://doi.org/10.1016/0022-2836(73)90066-1" @default.
• W2031808788 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/4585979" @default.
• W2031808788 hasPublicationYear "1973" @default.
• W2031808788 type Work @default.
• W2031808788 sameAs 2031808788 @default.
• W2031808788 citedByCount "22" @default.
• W2031808788 countsByYear W20318087882016 @default.
• W2031808788 countsByYear W20318087882018 @default.
• W2031808788 crossrefType "journal-article" @default.
• W2031808788 hasAuthorship W2031808788A5028220132 @default.
• W2031808788 hasAuthorship W2031808788A5068364757 @default.
• W2031808788 hasAuthorship W2031808788A5070876441 @default.
• W2031808788 hasConcept C104317684 @default.
• W2031808788 hasConcept C112950240 @default.
• W2031808788 hasConcept C12554922 @default.
• W2031808788 hasConcept C12590798 @default.
• W2031808788 hasConcept C13052165 @default.
• W2031808788 hasConcept C159047783 @default.
• W2031808788 hasConcept C178790620 @default.
• W2031808788 hasConcept C185592680 @default.
• W2031808788 hasConcept C191897082 @default.
• W2031808788 hasConcept C192562407 @default.
• W2031808788 hasConcept C198268994 @default.
• W2031808788 hasConcept C24586158 @default.
• W2031808788 hasConcept C2776441376 @default.
• W2031808788 hasConcept C32909587 @default.
• W2031808788 hasConcept C33947775 @default.
• W2031808788 hasConcept C54355233 @default.
• W2031808788 hasConcept C547475151 @default.
• W2031808788 hasConcept C552990157 @default.
• W2031808788 hasConcept C58337764 @default.
• W2031808788 hasConcept C64241487 @default.
• W2031808788 hasConcept C73573662 @default.
• W2031808788 hasConcept C7452308 @default.
• W2031808788 hasConcept C86803240 @default.
• W2031808788 hasConceptScore W2031808788C104317684 @default.
• W2031808788 hasConceptScore W2031808788C112950240 @default.
• W2031808788 hasConceptScore W2031808788C12554922 @default.
• W2031808788 hasConceptScore W2031808788C12590798 @default.
• W2031808788 hasConceptScore W2031808788C13052165 @default.
• W2031808788 hasConceptScore W2031808788C159047783 @default.
• W2031808788 hasConceptScore W2031808788C178790620 @default.
• W2031808788 hasConceptScore W2031808788C185592680 @default.
• W2031808788 hasConceptScore W2031808788C191897082 @default.
• W2031808788 hasConceptScore W2031808788C192562407 @default.
• W2031808788 hasConceptScore W2031808788C198268994 @default.
• W2031808788 hasConceptScore W2031808788C24586158 @default.
• W2031808788 hasConceptScore W2031808788C2776441376 @default.
• W2031808788 hasConceptScore W2031808788C32909587 @default.
• W2031808788 hasConceptScore W2031808788C33947775 @default.
• W2031808788 hasConceptScore W2031808788C54355233 @default.
• W2031808788 hasConceptScore W2031808788C547475151 @default.
• W2031808788 hasConceptScore W2031808788C552990157 @default.
• W2031808788 hasConceptScore W2031808788C58337764 @default.
• W2031808788 hasConceptScore W2031808788C64241487 @default.
• W2031808788 hasConceptScore W2031808788C73573662 @default.
• W2031808788 hasConceptScore W2031808788C7452308 @default.
• W2031808788 hasConceptScore W2031808788C86803240 @default.
• W2031808788 hasLocation W20318087881 @default.
• W2031808788 hasLocation W20318087882 @default.
• W2031808788 hasOpenAccess W2031808788 @default.
• W2031808788 hasPrimaryLocation W20318087881 @default.
• W2031808788 hasRelatedWork W1738494756 @default.
• W2031808788 hasRelatedWork W1980997045 @default.
• W2031808788 hasRelatedWork W2024411575 @default.
• W2031808788 hasRelatedWork W2048009452 @default.
• W2031808788 hasRelatedWork W2050304986 @default.
• W2031808788 hasRelatedWork W2058314271 @default.
• W2031808788 hasRelatedWork W2062722774 @default.

• next