FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2031828946> ?p ?o ?g. }

• W2031828946 endingPage "805" @default.
• W2031828946 startingPage "801" @default.
• W2031828946 abstract "In plants, the mechanism by which RNA can induce de novo cytosine methylation of homologous DNA is poorly understood. Cytosines in all sequence contexts become modified in response to RNA signals. Recent work has implicated the de novo DNA methyltransferases (DMTases), DRM1 and DRM2, in establishing RNA-directed methylation of the constitutive nopaline synthase promoter, as well as the DMTase MET1 and the putative histone deacetylase HDA6 in maintaining or enhancing CpG methylation induced by RNA. Despite the identification of enzymes that catalyze epigenetic modifications in response to RNA signals, it is unclear how RNA targets DNA for methylation. A screen for mutants defective in RNA-directed DNA methylation identified a novel putative chromatin-remodeling protein, DRD1. This protein belongs to a previously undefined, plant-specific subfamily of SWI2/SNF2-like proteins most similar to the RAD54/ATRX subfamily. In drd1 mutants, RNA-induced non-CpG methylation is almost eliminated at a target promoter, resulting in reactivation, whereas methylation of centromeric and rDNA repeats is unaffected. Thus, unlike the SNF2-like proteins DDM1/Lsh1 and ATRX, which regulate methylation of repetitive sequences, DRD1 is not a global regulator of cytosine methylation. DRD1 is the first SNF2-like protein implicated in an RNA-guided, epigenetic modification of the genome." @default.
• W2031828946 created "2016-06-24" @default.
• W2031828946 creator A5031570460 @default.
• W2031828946 creator A5056134549 @default.
• W2031828946 creator A5069041693 @default.
• W2031828946 creator A5076046328 @default.
• W2031828946 creator A5080264876 @default.
• W2031828946 creator A5080392675 @default.
• W2031828946 date "2004-05-01" @default.
• W2031828946 modified "2023-10-11" @default.
• W2031828946 title "Involvement of Putative SNF2 Chromatin Remodeling Protein DRD1 in RNA-Directed DNA Methylation" @default.
• W2031828946 cites W1550720320 @default.
• W2031828946 cites W1557790541 @default.
• W2031828946 cites W1838266191 @default.
• W2031828946 cites W1993257254 @default.
• W2031828946 cites W2001476164 @default.
• W2031828946 cites W2006895915 @default.
• W2031828946 cites W2012865420 @default.
• W2031828946 cites W2019896138 @default.
• W2031828946 cites W2052639867 @default.
• W2031828946 cites W2056681043 @default.
• W2031828946 cites W2084169030 @default.
• W2031828946 cites W2087874602 @default.
• W2031828946 cites W2087885007 @default.
• W2031828946 cites W2109458502 @default.
• W2031828946 cites W2116122104 @default.
• W2031828946 cites W2136796186 @default.
• W2031828946 cites W2137483650 @default.
• W2031828946 cites W2142785868 @default.
• W2031828946 cites W2153327762 @default.
• W2031828946 cites W2165834716 @default.
• W2031828946 cites W2171067881 @default.
• W2031828946 doi "https://doi.org/10.1016/j.cub.2004.04.037" @default.
• W2031828946 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15120073" @default.
• W2031828946 hasPublicationYear "2004" @default.
• W2031828946 type Work @default.
• W2031828946 sameAs 2031828946 @default.
• W2031828946 citedByCount "284" @default.
• W2031828946 countsByYear W20318289462012 @default.
• W2031828946 countsByYear W20318289462013 @default.
• W2031828946 countsByYear W20318289462014 @default.
• W2031828946 countsByYear W20318289462015 @default.
• W2031828946 countsByYear W20318289462016 @default.
• W2031828946 countsByYear W20318289462017 @default.
• W2031828946 countsByYear W20318289462018 @default.
• W2031828946 countsByYear W20318289462019 @default.
• W2031828946 countsByYear W20318289462020 @default.
• W2031828946 countsByYear W20318289462021 @default.
• W2031828946 countsByYear W20318289462022 @default.
• W2031828946 countsByYear W20318289462023 @default.
• W2031828946 crossrefType "journal-article" @default.
• W2031828946 hasAuthorship W2031828946A5031570460 @default.
• W2031828946 hasAuthorship W2031828946A5056134549 @default.
• W2031828946 hasAuthorship W2031828946A5069041693 @default.
• W2031828946 hasAuthorship W2031828946A5076046328 @default.
• W2031828946 hasAuthorship W2031828946A5080264876 @default.
• W2031828946 hasAuthorship W2031828946A5080392675 @default.
• W2031828946 hasBestOaLocation W20318289461 @default.
• W2031828946 hasConcept C104317684 @default.
• W2031828946 hasConcept C150194340 @default.
• W2031828946 hasConcept C153911025 @default.
• W2031828946 hasConcept C163002167 @default.
• W2031828946 hasConcept C167227067 @default.
• W2031828946 hasConcept C190727270 @default.
• W2031828946 hasConcept C21786251 @default.
• W2031828946 hasConcept C22709980 @default.
• W2031828946 hasConcept C33288867 @default.
• W2031828946 hasConcept C37080517 @default.
• W2031828946 hasConcept C54355233 @default.
• W2031828946 hasConcept C552990157 @default.
• W2031828946 hasConcept C67705224 @default.
• W2031828946 hasConcept C83640560 @default.
• W2031828946 hasConcept C86803240 @default.
• W2031828946 hasConcept C91965660 @default.
• W2031828946 hasConceptScore W2031828946C104317684 @default.
• W2031828946 hasConceptScore W2031828946C150194340 @default.
• W2031828946 hasConceptScore W2031828946C153911025 @default.
• W2031828946 hasConceptScore W2031828946C163002167 @default.
• W2031828946 hasConceptScore W2031828946C167227067 @default.
• W2031828946 hasConceptScore W2031828946C190727270 @default.
• W2031828946 hasConceptScore W2031828946C21786251 @default.
• W2031828946 hasConceptScore W2031828946C22709980 @default.
• W2031828946 hasConceptScore W2031828946C33288867 @default.
• W2031828946 hasConceptScore W2031828946C37080517 @default.
• W2031828946 hasConceptScore W2031828946C54355233 @default.
• W2031828946 hasConceptScore W2031828946C552990157 @default.
• W2031828946 hasConceptScore W2031828946C67705224 @default.
• W2031828946 hasConceptScore W2031828946C83640560 @default.
• W2031828946 hasConceptScore W2031828946C86803240 @default.
• W2031828946 hasConceptScore W2031828946C91965660 @default.
• W2031828946 hasIssue "9" @default.
• W2031828946 hasLocation W20318289461 @default.
• W2031828946 hasLocation W20318289462 @default.
• W2031828946 hasLocation W20318289463 @default.
• W2031828946 hasOpenAccess W2031828946 @default.
• W2031828946 hasPrimaryLocation W20318289461 @default.
• W2031828946 hasRelatedWork W107193064 @default.
• W2031828946 hasRelatedWork W1885638897 @default.

• next