FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2031854239> ?p ?o ?g. }

• W2031854239 endingPage "601" @default.
• W2031854239 startingPage "594" @default.
• W2031854239 abstract "Extracellular matrices (ECMs) play an important role as components of basement membrane of normal human skin and in migrating epidermal cells in wound healing. We investigated the effects of various ECMs on human keratinocyte adhesion and growth as well as on its secretion and deposition of fibronectin (FN) in vitro using a serum-free, low-calcium culture system. Since cell adhesion is the first step of cell growth, we performed cell adhesion assay for 14 h. Human keratinocytes adhered best on FN and less well on types I/III collagen, type IV collagen, and heparan sulfate proteoglycan (HSPG) as compared with bovine serum albumin (BSA) (control) or laminin (La). Cell growth assayed for 7-8 days on the dishes coated with various extracellular matrices revealed significantly increased keratinocyte growth on FN and on types I/III collagen in comparison with that on type IV collagen, HSPG, BSA (control), or La. Morphology of keratinocytes and of their colonies on FN and types I/III collagen was strikingly different from that of the control; the colonies were not so compact as in the control, but rather loose and larger; each keratinocyte was spread out more on these substrata. These morphologic features seemed to correlate with the increased keratinocyte growth on these extracellular matrices. Both immunofluorescence study for FN with keratinocytes in 8-day culture on various extracellular matrices and enzyme-linked immunosorbent assay for FN measurement on substratum or in conditioned medium with keratinocytes in 5-day culture demonstrated that extracellular matrices modulated the secretion and deposition of FN by human keratinocytes in culture; the keratinocyte growth correlated with the amount of FN detected on substratum but not with that in medium. Based on the results of the present investigation, we think that the growth of human keratinocytes depends on the amount of FN on substratum." @default.
• W2031854239 created "2016-06-24" @default.
• W2031854239 creator A5012976720 @default.
• W2031854239 creator A5019368274 @default.
• W2031854239 creator A5051390214 @default.
• W2031854239 creator A5057881988 @default.
• W2031854239 creator A5076519412 @default.
• W2031854239 date "1987-05-01" @default.
• W2031854239 modified "2023-09-27" @default.
• W2031854239 title "Effects of Extracellular Matrices on Human Keratinocyte Adhesion and Growth and on its Secretion and Deposition of Fibronectin in Culture" @default.
• W2031854239 cites W15289797 @default.
• W2031854239 cites W1967194093 @default.
• W2031854239 cites W1978094951 @default.
• W2031854239 cites W1980617596 @default.
• W2031854239 cites W1986051450 @default.
• W2031854239 cites W1994150598 @default.
• W2031854239 cites W2000777523 @default.
• W2031854239 cites W2002337023 @default.
• W2031854239 cites W2005858509 @default.
• W2031854239 cites W2013390456 @default.
• W2031854239 cites W2017553979 @default.
• W2031854239 cites W2024373128 @default.
• W2031854239 cites W2024973598 @default.
• W2031854239 cites W2031393274 @default.
• W2031854239 cites W2031768006 @default.
• W2031854239 cites W2036190487 @default.
• W2031854239 cites W2036517814 @default.
• W2031854239 cites W2040830239 @default.
• W2031854239 cites W2050612375 @default.
• W2031854239 cites W2056506461 @default.
• W2031854239 cites W2059102955 @default.
• W2031854239 cites W2060335268 @default.
• W2031854239 cites W2063753069 @default.
• W2031854239 cites W2065723241 @default.
• W2031854239 cites W2069651236 @default.
• W2031854239 cites W2070827212 @default.
• W2031854239 cites W2074029723 @default.
• W2031854239 cites W2078067897 @default.
• W2031854239 cites W2086673242 @default.
• W2031854239 cites W2094807512 @default.
• W2031854239 cites W2103669145 @default.
• W2031854239 cites W2130611295 @default.
• W2031854239 cites W2159826803 @default.
• W2031854239 doi "https://doi.org/10.1111/1523-1747.ep12470207" @default.
• W2031854239 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2437213" @default.
• W2031854239 hasPublicationYear "1987" @default.
• W2031854239 type Work @default.
• W2031854239 sameAs 2031854239 @default.
• W2031854239 citedByCount "48" @default.
• W2031854239 countsByYear W20318542392019 @default.
• W2031854239 countsByYear W20318542392020 @default.
• W2031854239 crossrefType "journal-article" @default.
• W2031854239 hasAuthorship W2031854239A5012976720 @default.
• W2031854239 hasAuthorship W2031854239A5019368274 @default.
• W2031854239 hasAuthorship W2031854239A5051390214 @default.
• W2031854239 hasAuthorship W2031854239A5057881988 @default.
• W2031854239 hasAuthorship W2031854239A5076519412 @default.
• W2031854239 hasConcept C1491633281 @default.
• W2031854239 hasConcept C153911025 @default.
• W2031854239 hasConcept C178790620 @default.
• W2031854239 hasConcept C185592680 @default.
• W2031854239 hasConcept C189165786 @default.
• W2031854239 hasConcept C202751555 @default.
• W2031854239 hasConcept C2776193487 @default.
• W2031854239 hasConcept C2777074287 @default.
• W2031854239 hasConcept C2777107211 @default.
• W2031854239 hasConcept C2779814568 @default.
• W2031854239 hasConcept C28406088 @default.
• W2031854239 hasConcept C49039625 @default.
• W2031854239 hasConcept C54355233 @default.
• W2031854239 hasConcept C55493867 @default.
• W2031854239 hasConcept C81885089 @default.
• W2031854239 hasConcept C84416704 @default.
• W2031854239 hasConcept C85789140 @default.
• W2031854239 hasConcept C86492073 @default.
• W2031854239 hasConcept C86803240 @default.
• W2031854239 hasConcept C95444343 @default.
• W2031854239 hasConceptScore W2031854239C1491633281 @default.
• W2031854239 hasConceptScore W2031854239C153911025 @default.
• W2031854239 hasConceptScore W2031854239C178790620 @default.
• W2031854239 hasConceptScore W2031854239C185592680 @default.
• W2031854239 hasConceptScore W2031854239C189165786 @default.
• W2031854239 hasConceptScore W2031854239C202751555 @default.
• W2031854239 hasConceptScore W2031854239C2776193487 @default.
• W2031854239 hasConceptScore W2031854239C2777074287 @default.
• W2031854239 hasConceptScore W2031854239C2777107211 @default.
• W2031854239 hasConceptScore W2031854239C2779814568 @default.
• W2031854239 hasConceptScore W2031854239C28406088 @default.
• W2031854239 hasConceptScore W2031854239C49039625 @default.
• W2031854239 hasConceptScore W2031854239C54355233 @default.
• W2031854239 hasConceptScore W2031854239C55493867 @default.
• W2031854239 hasConceptScore W2031854239C81885089 @default.
• W2031854239 hasConceptScore W2031854239C84416704 @default.
• W2031854239 hasConceptScore W2031854239C85789140 @default.
• W2031854239 hasConceptScore W2031854239C86492073 @default.
• W2031854239 hasConceptScore W2031854239C86803240 @default.
• W2031854239 hasConceptScore W2031854239C95444343 @default.
• W2031854239 hasIssue "5" @default.

• next