FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2031859897> ?p ?o ?g. }

• W2031859897 endingPage "167" @default.
• W2031859897 startingPage "157" @default.
• W2031859897 abstract "To identify the predictive markers associated with chemotherapy sensitivity, especially those producing pathological complete response (pCR) following neoadjuvant chemotherapy (NACT) in patients with locally advanced breast cancer.Core needle biopsy of 50 locally advanced breast cancer patients was analysed for histopathology, grade, oestrogen receptor, progesterone receptor, HER2, Ki-67, p53, Bcl-2, and BAX before starting NACT. This was correlated with response to NACT using Response Evaluation Criteria in Solid Tumours criteria.The mean tumour reduction rate per chemotherapy cycle was significantly higher in BAX-positive (p = 0.01) and Bcl-2-negative (p = 0.04) tumours. BAX expression significantly (p = 0.043) correlated with a response of an at least 30% reduction in tumour size post-NACT on multivariate analysis. A significant relationship was seen between loss of Bcl-2 expression and pCR on univariate (p = 0.048) analysis. Overall, all of the above 12 parameters had 30.4% and 28.5% success in predicting clinical complete response and pCR, respectively, by the Cox and Snell formula.Of all parameters examined, only the apoptosis-related genes (Bcl-2 and BAX) seemed to exert some influence on the response to NACT, and neither by itself was sufficient to predict pCR; however, 50 patients is not sufficient to simultaneously analyse several predictive markers." @default.
• W2031859897 created "2016-06-24" @default.
• W2031859897 creator A5053862715 @default.
• W2031859897 creator A5057131771 @default.
• W2031859897 creator A5064118548 @default.
• W2031859897 creator A5065509408 @default.
• W2031859897 creator A5084833463 @default.
• W2031859897 date "2010-10-01" @default.
• W2031859897 modified "2023-10-16" @default.
• W2031859897 title "Assessment of Predictive Markers of Response to Neoadjuvant Chemotherapy in Breast Cancer" @default.
• W2031859897 cites W1955397179 @default.
• W2031859897 cites W1977131634 @default.
• W2031859897 cites W1984328080 @default.
• W2031859897 cites W1989698903 @default.
• W2031859897 cites W1993488798 @default.
• W2031859897 cites W1999480135 @default.
• W2031859897 cites W2000557631 @default.
• W2031859897 cites W2015960413 @default.
• W2031859897 cites W2043630729 @default.
• W2031859897 cites W2055679225 @default.
• W2031859897 cites W2057084727 @default.
• W2031859897 cites W2058681718 @default.
• W2031859897 cites W2062421538 @default.
• W2031859897 cites W2066377591 @default.
• W2031859897 cites W2067578647 @default.
• W2031859897 cites W2078647713 @default.
• W2031859897 cites W2082462313 @default.
• W2031859897 cites W2083803850 @default.
• W2031859897 cites W2100634952 @default.
• W2031859897 cites W2109079833 @default.
• W2031859897 cites W2109462843 @default.
• W2031859897 cites W2120861328 @default.
• W2031859897 cites W2122449313 @default.
• W2031859897 cites W2123089413 @default.
• W2031859897 cites W2125729597 @default.
• W2031859897 cites W2138822460 @default.
• W2031859897 cites W2140654333 @default.
• W2031859897 cites W2140945784 @default.
• W2031859897 cites W2143625559 @default.
• W2031859897 cites W2162760540 @default.
• W2031859897 doi "https://doi.org/10.1016/s1015-9584(11)60001-8" @default.
• W2031859897 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21377101" @default.
• W2031859897 hasPublicationYear "2010" @default.
• W2031859897 type Work @default.
• W2031859897 sameAs 2031859897 @default.
• W2031859897 citedByCount "8" @default.
• W2031859897 countsByYear W20318598972012 @default.
• W2031859897 countsByYear W20318598972013 @default.
• W2031859897 countsByYear W20318598972014 @default.
• W2031859897 countsByYear W20318598972015 @default.
• W2031859897 countsByYear W20318598972017 @default.
• W2031859897 countsByYear W20318598972018 @default.
• W2031859897 crossrefType "journal-article" @default.
• W2031859897 hasAuthorship W2031859897A5053862715 @default.
• W2031859897 hasAuthorship W2031859897A5057131771 @default.
• W2031859897 hasAuthorship W2031859897A5064118548 @default.
• W2031859897 hasAuthorship W2031859897A5065509408 @default.
• W2031859897 hasAuthorship W2031859897A5084833463 @default.
• W2031859897 hasConcept C121608353 @default.
• W2031859897 hasConcept C126322002 @default.
• W2031859897 hasConcept C142724271 @default.
• W2031859897 hasConcept C143998085 @default.
• W2031859897 hasConcept C144301174 @default.
• W2031859897 hasConcept C207886595 @default.
• W2031859897 hasConcept C2775934546 @default.
• W2031859897 hasConcept C2776694085 @default.
• W2031859897 hasConcept C2780521871 @default.
• W2031859897 hasConcept C3019096185 @default.
• W2031859897 hasConcept C38180746 @default.
• W2031859897 hasConcept C530470458 @default.
• W2031859897 hasConcept C544855455 @default.
• W2031859897 hasConcept C71924100 @default.
• W2031859897 hasConcept C84606932 @default.
• W2031859897 hasConcept C98717036 @default.
• W2031859897 hasConceptScore W2031859897C121608353 @default.
• W2031859897 hasConceptScore W2031859897C126322002 @default.
• W2031859897 hasConceptScore W2031859897C142724271 @default.
• W2031859897 hasConceptScore W2031859897C143998085 @default.
• W2031859897 hasConceptScore W2031859897C144301174 @default.
• W2031859897 hasConceptScore W2031859897C207886595 @default.
• W2031859897 hasConceptScore W2031859897C2775934546 @default.
• W2031859897 hasConceptScore W2031859897C2776694085 @default.
• W2031859897 hasConceptScore W2031859897C2780521871 @default.
• W2031859897 hasConceptScore W2031859897C3019096185 @default.
• W2031859897 hasConceptScore W2031859897C38180746 @default.
• W2031859897 hasConceptScore W2031859897C530470458 @default.
• W2031859897 hasConceptScore W2031859897C544855455 @default.
• W2031859897 hasConceptScore W2031859897C71924100 @default.
• W2031859897 hasConceptScore W2031859897C84606932 @default.
• W2031859897 hasConceptScore W2031859897C98717036 @default.
• W2031859897 hasIssue "4" @default.
• W2031859897 hasLocation W20318598971 @default.
• W2031859897 hasLocation W20318598972 @default.
• W2031859897 hasOpenAccess W2031859897 @default.
• W2031859897 hasPrimaryLocation W20318598971 @default.
• W2031859897 hasRelatedWork W2052163941 @default.
• W2031859897 hasRelatedWork W2348152691 @default.
• W2031859897 hasRelatedWork W2358931612 @default.

• next