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• W2031878658 abstract "This study describes γ-imaging of the secondary tumors from the transplanted human fetal striatum neural stem cells-derived primary tumor cells in nude mice. The subcutaneous primary tumors were detected to express integrin αvβ3, and the corresponding cells were isolated and enriched in vitro, then transplanted to the nude mice. The technetium-99m-labeled Arg-Gly-Asp peptide, with high affinity to integrin αvβ3, was prepared for biodistribution and γ-imaging. The secondary tumors were readily visualized at 1-h postinjection, and the tumor uptake of radiotracer was similar to that of positive control animals transplanted with U87MG human glioma cells. The tumor specificity of radiotracer was demonstrated by blocking experiment. We concluded that γ-imaging is a promising approach in imaging the tumorigenesis of transplanted stem cells in vivo." @default.
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• W2031878658 date "2008-07-02" @default.
• W2031878658 modified "2023-09-24" @default.
• W2031878658 title "In vivo gamma imaging of the secondary tumors of transplanted human fetal striatum neural stem cells-derived primary tumor cells" @default.
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• W2031878658 doi "https://doi.org/10.1097/wnr.0b013e328303c020" @default.
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