Matches in SemOpenAlex for { <https://semopenalex.org/work/W2031894783> ?p ?o ?g. }
- W2031894783 endingPage "914" @default.
- W2031894783 startingPage "905" @default.
- W2031894783 abstract "Peptides based on cell-adhesive regions of fibronectin, Arg-Gly-Asp-Ser (RGDS), and vitronectin, Arg-Gly-Asp-Val (RGDV), were covalently bound to a polyurethane backbone via amide bonds. Nuclear magnetic resonance (NMR) and Fourier-transform infrared (FTIR) spectroscopies were used to monitor the reactions. The amount of grafted peptide was determined by amino acid analysis. X-ray photoelectron spectroscopy (XPS) suggested the presence of the grafted peptide at the polymer-air interface in vacuo. Dynamic contact angle analysis showed that, in water, the peptide-grafted polyurethane surfaces were more polar than the underivatized polyurethane indicating enrichment of peptide groups at the surface. The attachment and spreading of human umbilical vein endothelial cells (HUVECs) on the underivatized and peptide-grafted polyurethanes was investigated. The GRGDSY- and GRGDVY-grafted substrates supported cell adhesion and spreading even without serum in the culture medium. The GRGDVY-grafted substrate supported a larger number of adherent cells and a higher extent of cell spreading than the GRGDSY-grafted substrate. These RGD-containing peptide-grafted polyurethane copolymers may be useful in providing an easily prepared celladhesive substrate for various biomaterial applications." @default.
- W2031894783 created "2016-06-24" @default.
- W2031894783 creator A5006321055 @default.
- W2031894783 creator A5021289418 @default.
- W2031894783 creator A5037893640 @default.
- W2031894783 creator A5044816603 @default.
- W2031894783 creator A5052118000 @default.
- W2031894783 creator A5080669638 @default.
- W2031894783 date "1992-01-01" @default.
- W2031894783 modified "2023-10-18" @default.
- W2031894783 title "Endothelial cell adhesion on polyurethanes containing covalently attached RGD-peptides" @default.
- W2031894783 cites W1566157726 @default.
- W2031894783 cites W1590204800 @default.
- W2031894783 cites W1982691790 @default.
- W2031894783 cites W1983564694 @default.
- W2031894783 cites W1987568997 @default.
- W2031894783 cites W2006464022 @default.
- W2031894783 cites W2011659304 @default.
- W2031894783 cites W2046363565 @default.
- W2031894783 cites W2054479070 @default.
- W2031894783 cites W2056875440 @default.
- W2031894783 cites W2058570720 @default.
- W2031894783 cites W2071453141 @default.
- W2031894783 cites W2081452775 @default.
- W2031894783 cites W2081603322 @default.
- W2031894783 cites W2098400443 @default.
- W2031894783 cites W2169947138 @default.
- W2031894783 cites W2399310390 @default.
- W2031894783 cites W2418438446 @default.
- W2031894783 doi "https://doi.org/10.1016/0142-9612(92)90113-3" @default.
- W2031894783 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1477259" @default.
- W2031894783 hasPublicationYear "1992" @default.
- W2031894783 type Work @default.
- W2031894783 sameAs 2031894783 @default.
- W2031894783 citedByCount "130" @default.
- W2031894783 countsByYear W20318947832012 @default.
- W2031894783 countsByYear W20318947832013 @default.
- W2031894783 countsByYear W20318947832014 @default.
- W2031894783 countsByYear W20318947832015 @default.
- W2031894783 countsByYear W20318947832016 @default.
- W2031894783 countsByYear W20318947832017 @default.
- W2031894783 countsByYear W20318947832018 @default.
- W2031894783 countsByYear W20318947832019 @default.
- W2031894783 countsByYear W20318947832020 @default.
- W2031894783 countsByYear W20318947832021 @default.
- W2031894783 countsByYear W20318947832022 @default.
- W2031894783 countsByYear W20318947832023 @default.
- W2031894783 crossrefType "journal-article" @default.
- W2031894783 hasAuthorship W2031894783A5006321055 @default.
- W2031894783 hasAuthorship W2031894783A5021289418 @default.
- W2031894783 hasAuthorship W2031894783A5037893640 @default.
- W2031894783 hasAuthorship W2031894783A5044816603 @default.
- W2031894783 hasAuthorship W2031894783A5052118000 @default.
- W2031894783 hasAuthorship W2031894783A5080669638 @default.
- W2031894783 hasConcept C111368507 @default.
- W2031894783 hasConcept C12554922 @default.
- W2031894783 hasConcept C127313418 @default.
- W2031894783 hasConcept C127413603 @default.
- W2031894783 hasConcept C1491633281 @default.
- W2031894783 hasConcept C159985019 @default.
- W2031894783 hasConcept C160892712 @default.
- W2031894783 hasConcept C171250308 @default.
- W2031894783 hasConcept C178790620 @default.
- W2031894783 hasConcept C180577832 @default.
- W2031894783 hasConcept C185592680 @default.
- W2031894783 hasConcept C188027245 @default.
- W2031894783 hasConcept C192562407 @default.
- W2031894783 hasConcept C2777289219 @default.
- W2031894783 hasConcept C2778414984 @default.
- W2031894783 hasConcept C2779281246 @default.
- W2031894783 hasConcept C2779578285 @default.
- W2031894783 hasConcept C42360764 @default.
- W2031894783 hasConcept C55493867 @default.
- W2031894783 hasConcept C6556556 @default.
- W2031894783 hasConcept C84416704 @default.
- W2031894783 hasConcept C85789140 @default.
- W2031894783 hasConcept C86492073 @default.
- W2031894783 hasConcept C86803240 @default.
- W2031894783 hasConceptScore W2031894783C111368507 @default.
- W2031894783 hasConceptScore W2031894783C12554922 @default.
- W2031894783 hasConceptScore W2031894783C127313418 @default.
- W2031894783 hasConceptScore W2031894783C127413603 @default.
- W2031894783 hasConceptScore W2031894783C1491633281 @default.
- W2031894783 hasConceptScore W2031894783C159985019 @default.
- W2031894783 hasConceptScore W2031894783C160892712 @default.
- W2031894783 hasConceptScore W2031894783C171250308 @default.
- W2031894783 hasConceptScore W2031894783C178790620 @default.
- W2031894783 hasConceptScore W2031894783C180577832 @default.
- W2031894783 hasConceptScore W2031894783C185592680 @default.
- W2031894783 hasConceptScore W2031894783C188027245 @default.
- W2031894783 hasConceptScore W2031894783C192562407 @default.
- W2031894783 hasConceptScore W2031894783C2777289219 @default.
- W2031894783 hasConceptScore W2031894783C2778414984 @default.
- W2031894783 hasConceptScore W2031894783C2779281246 @default.
- W2031894783 hasConceptScore W2031894783C2779578285 @default.
- W2031894783 hasConceptScore W2031894783C42360764 @default.
- W2031894783 hasConceptScore W2031894783C55493867 @default.
- W2031894783 hasConceptScore W2031894783C6556556 @default.