Matches in SemOpenAlex for { <https://semopenalex.org/work/W2031916898> ?p ?o ?g. }
- W2031916898 endingPage "9813" @default.
- W2031916898 startingPage "9809" @default.
- W2031916898 abstract "cDNA encoding a hormone- and guanine nucleotide-stimulated adenylyl cyclase [ATP pyrophosphate-lyase (cyclizing), EC 4.6.1.1] (type 6) from rat liver and kidney has been cloned and expressed. This enzyme is stimulated by forskolin, guanosine 5'-[gamma-thio]triphosphate, and isoproterenol plus GTP but is not stimulated by beta gamma subunits of guanine nucleotide-binding proteins. A second form (type 5), which is 75% similar to type 6, has also been cloned. Both types 5 and 6 cDNAs have multiple messages. PCR-based detection of the mRNA for the type 5 and 6 enzymes indicates that both are widely distributed. Homology analyses indicate at least four distinct subfamilies of guanine nucleotide stimulatory protein-regulated adenylyl cyclases. Types 5 and 6 enzymes define one distinct subfamily of mammalian adenylyl cyclases. Diversity of one guanine nucleotide-binding protein-regulated effector may allow different modes of regulation of cell-surface signal transmission." @default.
- W2031916898 created "2016-06-24" @default.
- W2031916898 creator A5007552814 @default.
- W2031916898 creator A5015357235 @default.
- W2031916898 creator A5050538530 @default.
- W2031916898 creator A5065778793 @default.
- W2031916898 creator A5085059643 @default.
- W2031916898 date "1992-10-15" @default.
- W2031916898 modified "2023-10-15" @default.
- W2031916898 title "Two members of a widely expressed subfamily of hormone-stimulated adenylyl cyclases." @default.
- W2031916898 cites W1525041374 @default.
- W2031916898 cites W1559249470 @default.
- W2031916898 cites W1566362183 @default.
- W2031916898 cites W1569033208 @default.
- W2031916898 cites W1597493417 @default.
- W2031916898 cites W1965447347 @default.
- W2031916898 cites W1969583788 @default.
- W2031916898 cites W1981416199 @default.
- W2031916898 cites W1992444908 @default.
- W2031916898 cites W1995536774 @default.
- W2031916898 cites W1998023125 @default.
- W2031916898 cites W2000570602 @default.
- W2031916898 cites W2013978625 @default.
- W2031916898 cites W2026721784 @default.
- W2031916898 cites W2032979918 @default.
- W2031916898 cites W2039132145 @default.
- W2031916898 cites W2046155443 @default.
- W2031916898 cites W2070610716 @default.
- W2031916898 cites W2072417219 @default.
- W2031916898 cites W2074122548 @default.
- W2031916898 cites W2078817376 @default.
- W2031916898 cites W2087179850 @default.
- W2031916898 cites W2169503005 @default.
- W2031916898 cites W2221472711 @default.
- W2031916898 cites W2228799745 @default.
- W2031916898 cites W2467935456 @default.
- W2031916898 doi "https://doi.org/10.1073/pnas.89.20.9809" @default.
- W2031916898 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/50222" @default.
- W2031916898 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1409703" @default.
- W2031916898 hasPublicationYear "1992" @default.
- W2031916898 type Work @default.
- W2031916898 sameAs 2031916898 @default.
- W2031916898 citedByCount "159" @default.
- W2031916898 countsByYear W20319168982013 @default.
- W2031916898 countsByYear W20319168982014 @default.
- W2031916898 countsByYear W20319168982018 @default.
- W2031916898 countsByYear W20319168982019 @default.
- W2031916898 countsByYear W20319168982020 @default.
- W2031916898 countsByYear W20319168982022 @default.
- W2031916898 crossrefType "journal-article" @default.
- W2031916898 hasAuthorship W2031916898A5007552814 @default.
- W2031916898 hasAuthorship W2031916898A5015357235 @default.
- W2031916898 hasAuthorship W2031916898A5050538530 @default.
- W2031916898 hasAuthorship W2031916898A5065778793 @default.
- W2031916898 hasAuthorship W2031916898A5085059643 @default.
- W2031916898 hasBestOaLocation W20319168981 @default.
- W2031916898 hasConcept C104317684 @default.
- W2031916898 hasConcept C118716 @default.
- W2031916898 hasConcept C153911025 @default.
- W2031916898 hasConcept C170493617 @default.
- W2031916898 hasConcept C181199279 @default.
- W2031916898 hasConcept C187882448 @default.
- W2031916898 hasConcept C2777995097 @default.
- W2031916898 hasConcept C2778301229 @default.
- W2031916898 hasConcept C2779178603 @default.
- W2031916898 hasConcept C50929876 @default.
- W2031916898 hasConcept C512185932 @default.
- W2031916898 hasConcept C55493867 @default.
- W2031916898 hasConcept C69101867 @default.
- W2031916898 hasConcept C80631254 @default.
- W2031916898 hasConcept C86803240 @default.
- W2031916898 hasConceptScore W2031916898C104317684 @default.
- W2031916898 hasConceptScore W2031916898C118716 @default.
- W2031916898 hasConceptScore W2031916898C153911025 @default.
- W2031916898 hasConceptScore W2031916898C170493617 @default.
- W2031916898 hasConceptScore W2031916898C181199279 @default.
- W2031916898 hasConceptScore W2031916898C187882448 @default.
- W2031916898 hasConceptScore W2031916898C2777995097 @default.
- W2031916898 hasConceptScore W2031916898C2778301229 @default.
- W2031916898 hasConceptScore W2031916898C2779178603 @default.
- W2031916898 hasConceptScore W2031916898C50929876 @default.
- W2031916898 hasConceptScore W2031916898C512185932 @default.
- W2031916898 hasConceptScore W2031916898C55493867 @default.
- W2031916898 hasConceptScore W2031916898C69101867 @default.
- W2031916898 hasConceptScore W2031916898C80631254 @default.
- W2031916898 hasConceptScore W2031916898C86803240 @default.
- W2031916898 hasIssue "20" @default.
- W2031916898 hasLocation W20319168981 @default.
- W2031916898 hasLocation W20319168982 @default.
- W2031916898 hasLocation W20319168983 @default.
- W2031916898 hasLocation W20319168984 @default.
- W2031916898 hasOpenAccess W2031916898 @default.
- W2031916898 hasPrimaryLocation W20319168981 @default.
- W2031916898 hasRelatedWork W2058801184 @default.
- W2031916898 hasRelatedWork W2079349364 @default.
- W2031916898 hasRelatedWork W2083621684 @default.
- W2031916898 hasRelatedWork W2111526595 @default.
- W2031916898 hasRelatedWork W2117514208 @default.