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- W2031931331 abstract "Twelve years ago, the introduction of motile sperm organelle morphology examination led to the development of a modified intracytoplasmic sperm injection procedure called intracytoplasmic morphologically selected sperm injection (IMSI) in which a spermatozoon selected under high magnification instead of 400× magnification is injected into an oocyte. Several studies found no correlation between IMSI and early embryo development in terms of fertilization while others found an increase in the fertilization rate. Conflicting results regarding the rates of implantation, pregnancy and abortion were also reported. A significant increase in the rate of top-quality embryos on days 3 and 5 was reported by the majority of the studies, and few failed to demonstrate a relationship between IMSI and embryo quality. Because of the extent of the population sizes and the diverse approaches and motile sperm organelle morphology examination classifications used by the studies reported thus far, definite conclusions on the consequences of vacuoles on embryo development cannot be drawn. More randomized controlled studies conducted by independent groups on large series are still needed, not only to identify the populations of patients that could benefit from the IMSI, but also to determine the efficacy of IMSI over intracytoplasmic sperm injection on the improvement of pregnancy outcomes." @default.
- W2031931331 created "2016-06-24" @default.
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- W2031931331 date "2013-05-01" @default.
- W2031931331 modified "2023-10-14" @default.
- W2031931331 title "Intracytoplasmic morphologically selected sperm injection or intracytoplasmic sperm injection: where are we 12 years later?" @default.
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- W2031931331 doi "https://doi.org/10.1586/eog.13.12" @default.
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