FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2031933242> ?p ?o ?g. }

• W2031933242 endingPage "148" @default.
• W2031933242 startingPage "137" @default.
• W2031933242 abstract "Presbyopia, the inability to accommodate, affects almost everyone at middle age. Recently, it has been shown that there is a massive increase in the stiffness<footref rid=foot01>¹</footref> of the lens with age and, since the shape of the lens must change during accommodation, this could provide an explanation for presbyopia. In this review, we propose that presbyopia may be the earliest observable symptom of age-related nuclear (ARN) cataract. ARN cataract is a major cause of world blindness. The genesis of ARN cataract can be traced to the onset of a barrier within the lens at middle age. This barrier restricts the ability of small molecules, such as antioxidants, to penetrate into the centre of the lens leaving the proteins in this region susceptible to oxidation and post-translational modification. Major protein oxidation and colouration are the hallmarks of ARN cataract. We postulate that the onset of the barrier, and the hardening of the nucleus, are intimately linked. Specifically, we propose that progressive age-dependent hardening of the lens nucleus may be responsible for both presbyopia and ARN cataract." @default.
• W2031933242 created "2016-06-24" @default.
• W2031933242 creator A5032962662 @default.
• W2031933242 creator A5071312249 @default.
• W2031933242 date "2006-01-01" @default.
• W2031933242 modified "2023-09-26" @default.
• W2031933242 title "Presbyopia: The First Stage of Nuclear Cataract?" @default.
• W2031933242 cites W1162937925 @default.
• W2031933242 cites W148976868 @default.
• W2031933242 cites W1498327239 @default.
• W2031933242 cites W1501080875 @default.
• W2031933242 cites W1506118172 @default.
• W2031933242 cites W1509925174 @default.
• W2031933242 cites W1510128262 @default.
• W2031933242 cites W1563215534 @default.
• W2031933242 cites W163395888 @default.
• W2031933242 cites W1645482826 @default.
• W2031933242 cites W180231401 @default.
• W2031933242 cites W1860326127 @default.
• W2031933242 cites W1936380547 @default.
• W2031933242 cites W194357866 @default.
• W2031933242 cites W1964108639 @default.
• W2031933242 cites W1964381110 @default.
• W2031933242 cites W1967513516 @default.
• W2031933242 cites W1970589352 @default.
• W2031933242 cites W1970726904 @default.
• W2031933242 cites W1971284982 @default.
• W2031933242 cites W1971578516 @default.
• W2031933242 cites W1972198111 @default.
• W2031933242 cites W1973444843 @default.
• W2031933242 cites W1975474977 @default.
• W2031933242 cites W1975980571 @default.
• W2031933242 cites W1975995050 @default.
• W2031933242 cites W1977356903 @default.
• W2031933242 cites W1979067751 @default.
• W2031933242 cites W1983055388 @default.
• W2031933242 cites W1983895641 @default.
• W2031933242 cites W1985094420 @default.
• W2031933242 cites W1986591315 @default.
• W2031933242 cites W1987013731 @default.
• W2031933242 cites W1987014746 @default.
• W2031933242 cites W1987681547 @default.
• W2031933242 cites W1991369968 @default.
• W2031933242 cites W1994050512 @default.
• W2031933242 cites W1998023155 @default.
• W2031933242 cites W1998266668 @default.
• W2031933242 cites W1998316282 @default.
• W2031933242 cites W2001012162 @default.
• W2031933242 cites W2004617457 @default.
• W2031933242 cites W2006611969 @default.
• W2031933242 cites W2008381703 @default.
• W2031933242 cites W2009178659 @default.
• W2031933242 cites W2010772007 @default.
• W2031933242 cites W2017767274 @default.
• W2031933242 cites W2018019039 @default.
• W2031933242 cites W2018029767 @default.
• W2031933242 cites W2019058807 @default.
• W2031933242 cites W2019096786 @default.
• W2031933242 cites W2020765641 @default.
• W2031933242 cites W2023827068 @default.
• W2031933242 cites W2026368547 @default.
• W2031933242 cites W2030584905 @default.
• W2031933242 cites W2030900937 @default.
• W2031933242 cites W2032267632 @default.
• W2031933242 cites W2037371249 @default.
• W2031933242 cites W2040433272 @default.
• W2031933242 cites W2040792371 @default.
• W2031933242 cites W2041926981 @default.
• W2031933242 cites W2042569745 @default.
• W2031933242 cites W2044746839 @default.
• W2031933242 cites W2047255902 @default.
• W2031933242 cites W2047573391 @default.
• W2031933242 cites W2050438710 @default.
• W2031933242 cites W2050614422 @default.
• W2031933242 cites W2050820564 @default.
• W2031933242 cites W2051054352 @default.
• W2031933242 cites W2052487057 @default.
• W2031933242 cites W2053495306 @default.
• W2031933242 cites W2053530903 @default.
• W2031933242 cites W2056127891 @default.
• W2031933242 cites W2057423889 @default.
• W2031933242 cites W2059470236 @default.
• W2031933242 cites W2059678178 @default.
• W2031933242 cites W2060570977 @default.
• W2031933242 cites W2061269546 @default.
• W2031933242 cites W2062007365 @default.
• W2031933242 cites W2063743865 @default.
• W2031933242 cites W2066140320 @default.
• W2031933242 cites W2066303560 @default.
• W2031933242 cites W2066518963 @default.
• W2031933242 cites W2068882937 @default.
• W2031933242 cites W2070922533 @default.
• W2031933242 cites W2071306576 @default.
• W2031933242 cites W2071335303 @default.
• W2031933242 cites W2071839287 @default.
• W2031933242 cites W20752460 @default.
• W2031933242 cites W2079068897 @default.
• W2031933242 cites W2079516125 @default.

• next