Matches in SemOpenAlex for { <https://semopenalex.org/work/W2031982078> ?p ?o ?g. }
- W2031982078 endingPage "27" @default.
- W2031982078 startingPage "16" @default.
- W2031982078 abstract "Parkinson's disease is the second most common neurodegenerative disease, after Alzheimer's disease. Neuropathologically, it is characterized by the degeneration of populations of nerve cells that develop filamentous inclusions in the form of Lewy bodies and Lewy neurites. Recent work has shown that the filamentous inclusions of Parkinson's disease are made of the protein alpha-synuclein and that rare, familial forms of Parkinson's disease are caused by missense mutations in the alpha-synuclein gene. Besides Parkinson's disease, the filamentous inclusions of two additional neurodegenerative diseases, namely, dementia with Lewy bodies and multiple system atrophy, have also been found to be made of alpha-synuclein. Recombinant alpha-synuclein has been shown to assemble into filaments with similar morphologies to those found in the human diseases and with a cross-beta fiber diffraction pattern. The new work has established the alpha-synucleinopathies as a major class of neurodegenerative disease." @default.
- W2031982078 created "2016-06-24" @default.
- W2031982078 creator A5037379608 @default.
- W2031982078 creator A5037609259 @default.
- W2031982078 date "2006-01-25" @default.
- W2031982078 modified "2023-10-11" @default.
- W2031982078 title "The α-Synucleinopathies: Parkinson's Disease, Dementia with Lewy Bodies, and Multiple System Atrophy" @default.
- W2031982078 cites W1527671059 @default.
- W2031982078 cites W1587973572 @default.
- W2031982078 cites W1966360490 @default.
- W2031982078 cites W1968390598 @default.
- W2031982078 cites W1970122257 @default.
- W2031982078 cites W1972646996 @default.
- W2031982078 cites W1972665983 @default.
- W2031982078 cites W1973624256 @default.
- W2031982078 cites W1979786105 @default.
- W2031982078 cites W1986042913 @default.
- W2031982078 cites W1986625112 @default.
- W2031982078 cites W1987467412 @default.
- W2031982078 cites W1989999317 @default.
- W2031982078 cites W1990868007 @default.
- W2031982078 cites W1991130856 @default.
- W2031982078 cites W1999159261 @default.
- W2031982078 cites W1999893655 @default.
- W2031982078 cites W2001407922 @default.
- W2031982078 cites W2002506451 @default.
- W2031982078 cites W2007477251 @default.
- W2031982078 cites W2013313629 @default.
- W2031982078 cites W2014758938 @default.
- W2031982078 cites W2016816471 @default.
- W2031982078 cites W2018633688 @default.
- W2031982078 cites W2021555276 @default.
- W2031982078 cites W2021977313 @default.
- W2031982078 cites W2022628342 @default.
- W2031982078 cites W2024279546 @default.
- W2031982078 cites W2025399871 @default.
- W2031982078 cites W2027649342 @default.
- W2031982078 cites W2027820438 @default.
- W2031982078 cites W2031384224 @default.
- W2031982078 cites W2033904939 @default.
- W2031982078 cites W2034164574 @default.
- W2031982078 cites W2034210468 @default.
- W2031982078 cites W2035661230 @default.
- W2031982078 cites W2037396698 @default.
- W2031982078 cites W2040526078 @default.
- W2031982078 cites W2040706104 @default.
- W2031982078 cites W2040753345 @default.
- W2031982078 cites W2047206971 @default.
- W2031982078 cites W2048716049 @default.
- W2031982078 cites W2049819787 @default.
- W2031982078 cites W2050786534 @default.
- W2031982078 cites W2050922537 @default.
- W2031982078 cites W2063953430 @default.
- W2031982078 cites W2066155243 @default.
- W2031982078 cites W2068602144 @default.
- W2031982078 cites W2069288638 @default.
- W2031982078 cites W2070760404 @default.
- W2031982078 cites W2071087722 @default.
- W2031982078 cites W2071243806 @default.
- W2031982078 cites W2074649216 @default.
- W2031982078 cites W2076692782 @default.
- W2031982078 cites W2081392975 @default.
- W2031982078 cites W2084873065 @default.
- W2031982078 cites W2089193533 @default.
- W2031982078 cites W2090048744 @default.
- W2031982078 cites W2090988108 @default.
- W2031982078 cites W2091265794 @default.
- W2031982078 cites W2098441176 @default.
- W2031982078 cites W2099976784 @default.
- W2031982078 cites W2107451956 @default.
- W2031982078 cites W2109656063 @default.
- W2031982078 cites W2116597539 @default.
- W2031982078 cites W2130323165 @default.
- W2031982078 cites W2133068803 @default.
- W2031982078 cites W2150656456 @default.
- W2031982078 cites W2161334375 @default.
- W2031982078 cites W2165732672 @default.
- W2031982078 cites W2983107274 @default.
- W2031982078 doi "https://doi.org/10.1111/j.1749-6632.2000.tb06900.x" @default.
- W2031982078 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11193145" @default.
- W2031982078 hasPublicationYear "2006" @default.
- W2031982078 type Work @default.
- W2031982078 sameAs 2031982078 @default.
- W2031982078 citedByCount "424" @default.
- W2031982078 countsByYear W20319820782012 @default.
- W2031982078 countsByYear W20319820782013 @default.
- W2031982078 countsByYear W20319820782014 @default.
- W2031982078 countsByYear W20319820782015 @default.
- W2031982078 countsByYear W20319820782016 @default.
- W2031982078 countsByYear W20319820782017 @default.
- W2031982078 countsByYear W20319820782018 @default.
- W2031982078 countsByYear W20319820782019 @default.
- W2031982078 countsByYear W20319820782020 @default.
- W2031982078 countsByYear W20319820782021 @default.
- W2031982078 countsByYear W20319820782022 @default.
- W2031982078 countsByYear W20319820782023 @default.
- W2031982078 crossrefType "journal-article" @default.
- W2031982078 hasAuthorship W2031982078A5037379608 @default.