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- W2031998400 abstract "Biological systems possess inherent molecular recognition and self-assembly capabilities and are attractive templates for constructing complex material structures with molecular precision. Here we report the assembly of various nanoachitectures including nanoparticle arrays, hetero-nanoparticle architectures, and nanowires utilizing highly engineered M13 bacteriophage as templates. The genome of M13 phage can be rationally engineered to produce viral particles with distinct substrate-specific peptides expressed on the filamentous capsid and the ends, providing a generic template for programmable assembly of complex nanostructures. Phage clones with gold-binding motifs on the capsid and streptavidin-binding motifs at one end are created and used to assemble Au and CdSe nanocrytals into ordered one-dimensional arrays and more complex geometries. Initial studies show such nanoparticle arrays can further function as templates to nucleate highly conductive nanowires that are important for addressing/interconnecting individual nanostructures." @default.
- W2031998400 created "2016-06-24" @default.
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- W2031998400 date "2005-06-03" @default.
- W2031998400 modified "2023-10-16" @default.
- W2031998400 title "Programmable Assembly of Nanoarchitectures Using Genetically Engineered Viruses" @default.
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- W2031998400 doi "https://doi.org/10.1021/nl050795d" @default.
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