Matches in SemOpenAlex for { <https://semopenalex.org/work/W2032010060> ?p ?o ?g. }
- W2032010060 endingPage "816" @default.
- W2032010060 startingPage "805" @default.
- W2032010060 abstract "The aim of this article is to investigate the characteristics of a vial freeze-dried product as a function of the temperature at which the primary drying is carried out. The effect of the drying temperature and composition on the product appearance and final characteristics (apparent density and rehydratability) of pure substances (mannitol, sucrose, and dextran) has been studied: rehydratability is faster for the product freeze dried at lower temperature, when the structure of the product is more porous and softer; higher rehydration rates were also observed for samples obtained from lower initial concentration. In case of binary mixtures (mannitol and dextran, sucrose and dextran) the rehydratability gets worse when higher drying temperatures are used, whereas the relative composition has a smaller effect. Nevertheless, high drying temperatures are required to shorten the process, both in case of pure substances and in case of binary mixtures; thus, it is important to consider the process time–product quality relationship to choose the optimal drying temperature. Finally, we show that the freeze drying of mixtures can be easier and faster than that of one of the components alone; this is partly a consequence of the higher temperatures allowed, but it is evident that in some cases the drying kinetics can be higher even with the same process temperature." @default.
- W2032010060 created "2016-06-24" @default.
- W2032010060 creator A5056121539 @default.
- W2032010060 creator A5076792385 @default.
- W2032010060 creator A5082036312 @default.
- W2032010060 creator A5088853578 @default.
- W2032010060 date "2009-06-04" @default.
- W2032010060 modified "2023-09-23" @default.
- W2032010060 title "Freeze Drying of Pharmaceutical Excipients Close to Collapse Temperature: Influence of the Process Conditions on Process Time and Product Quality" @default.
- W2032010060 cites W155075061 @default.
- W2032010060 cites W1972596775 @default.
- W2032010060 cites W1986312111 @default.
- W2032010060 cites W1988752981 @default.
- W2032010060 cites W1997569985 @default.
- W2032010060 cites W2014528492 @default.
- W2032010060 cites W2016064225 @default.
- W2032010060 cites W2016275719 @default.
- W2032010060 cites W2017341540 @default.
- W2032010060 cites W2028883025 @default.
- W2032010060 cites W2033378134 @default.
- W2032010060 cites W2036754108 @default.
- W2032010060 cites W2043685190 @default.
- W2032010060 cites W2045616230 @default.
- W2032010060 cites W2045833357 @default.
- W2032010060 cites W2046120783 @default.
- W2032010060 cites W2048199422 @default.
- W2032010060 cites W2057997673 @default.
- W2032010060 cites W2061774732 @default.
- W2032010060 cites W2065308943 @default.
- W2032010060 cites W2066392189 @default.
- W2032010060 cites W2077680888 @default.
- W2032010060 cites W2100986250 @default.
- W2032010060 cites W2112095319 @default.
- W2032010060 cites W2149381364 @default.
- W2032010060 cites W4236040901 @default.
- W2032010060 doi "https://doi.org/10.1080/07373930902901646" @default.
- W2032010060 hasPublicationYear "2009" @default.
- W2032010060 type Work @default.
- W2032010060 sameAs 2032010060 @default.
- W2032010060 citedByCount "55" @default.
- W2032010060 countsByYear W20320100602012 @default.
- W2032010060 countsByYear W20320100602013 @default.
- W2032010060 countsByYear W20320100602014 @default.
- W2032010060 countsByYear W20320100602015 @default.
- W2032010060 countsByYear W20320100602016 @default.
- W2032010060 countsByYear W20320100602017 @default.
- W2032010060 countsByYear W20320100602018 @default.
- W2032010060 countsByYear W20320100602019 @default.
- W2032010060 countsByYear W20320100602020 @default.
- W2032010060 countsByYear W20320100602021 @default.
- W2032010060 countsByYear W20320100602022 @default.
- W2032010060 countsByYear W20320100602023 @default.
- W2032010060 crossrefType "journal-article" @default.
- W2032010060 hasAuthorship W2032010060A5056121539 @default.
- W2032010060 hasAuthorship W2032010060A5076792385 @default.
- W2032010060 hasAuthorship W2032010060A5082036312 @default.
- W2032010060 hasAuthorship W2032010060A5088853578 @default.
- W2032010060 hasBestOaLocation W20320100602 @default.
- W2032010060 hasConcept C111919701 @default.
- W2032010060 hasConcept C121332964 @default.
- W2032010060 hasConcept C127413603 @default.
- W2032010060 hasConcept C148898269 @default.
- W2032010060 hasConcept C162324750 @default.
- W2032010060 hasConcept C178790620 @default.
- W2032010060 hasConcept C185592680 @default.
- W2032010060 hasConcept C192562407 @default.
- W2032010060 hasConcept C2777339698 @default.
- W2032010060 hasConcept C2778445172 @default.
- W2032010060 hasConcept C2778597767 @default.
- W2032010060 hasConcept C34447519 @default.
- W2032010060 hasConcept C41008148 @default.
- W2032010060 hasConcept C42360764 @default.
- W2032010060 hasConcept C43617362 @default.
- W2032010060 hasConcept C62520636 @default.
- W2032010060 hasConcept C84199377 @default.
- W2032010060 hasConcept C89008666 @default.
- W2032010060 hasConcept C97355855 @default.
- W2032010060 hasConcept C98045186 @default.
- W2032010060 hasConceptScore W2032010060C111919701 @default.
- W2032010060 hasConceptScore W2032010060C121332964 @default.
- W2032010060 hasConceptScore W2032010060C127413603 @default.
- W2032010060 hasConceptScore W2032010060C148898269 @default.
- W2032010060 hasConceptScore W2032010060C162324750 @default.
- W2032010060 hasConceptScore W2032010060C178790620 @default.
- W2032010060 hasConceptScore W2032010060C185592680 @default.
- W2032010060 hasConceptScore W2032010060C192562407 @default.
- W2032010060 hasConceptScore W2032010060C2777339698 @default.
- W2032010060 hasConceptScore W2032010060C2778445172 @default.
- W2032010060 hasConceptScore W2032010060C2778597767 @default.
- W2032010060 hasConceptScore W2032010060C34447519 @default.
- W2032010060 hasConceptScore W2032010060C41008148 @default.
- W2032010060 hasConceptScore W2032010060C42360764 @default.
- W2032010060 hasConceptScore W2032010060C43617362 @default.
- W2032010060 hasConceptScore W2032010060C62520636 @default.
- W2032010060 hasConceptScore W2032010060C84199377 @default.
- W2032010060 hasConceptScore W2032010060C89008666 @default.
- W2032010060 hasConceptScore W2032010060C97355855 @default.
- W2032010060 hasConceptScore W2032010060C98045186 @default.