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- W2032017483 abstract "Previous work had demonstrated that chicken pituitaries contained a substance which was able to cause corticosterone synthesis by adrenals in vitro. In the present study chicken pituitary glands were assayed by the adrenal ascorbic acid-depletion method in hypophysectomized rats. It was found that perfect parallelism existed between the doses of 1.5–96.0 μg/100g body weight of chicken adenohypophyses and 0.4–10.0 mU of a standard mammalian ACTH. The data presented show that chicken pituitary glands contain relatively more ACTH than do those of rats. When assayed on hypophysectomized rats, perfect parallelism was demonstrated between extracts of 10, 20, and 40 chicken hypothalamic fragments and 0.4, 2.0, and 10.0 mU of the ACTH standard. Similar data were obtained on intact blocked rats. These results led to the conclusion that chicken hypothalami contain ACTH or an ACTH-like substance. No activity was present in extracts of chicken cerebral cortices which were used as control test substances." @default.
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- W2032017483 title "A study of ACTH and CRF in chickens" @default.
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- W2032017483 doi "https://doi.org/10.1016/0016-6480(70)90055-9" @default.
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