Matches in SemOpenAlex for { <https://semopenalex.org/work/W2032020785> ?p ?o ?g. }
Showing items 1 to 70 of
70
with 100 items per page.
- W2032020785 endingPage "194" @default.
- W2032020785 startingPage "189" @default.
- W2032020785 abstract "Abstract A new site-specific chemical delivery system (CDS) for propranolol was designed and investigated as a novel potential antiglaucoma agent. Effect of this compound, propranolone oxime ( 1 ), on the intraocular pressure (IOP) of rabbits was studied at two different concentrations (0.5% and 1.0%) by unilateral application to normal rabbits. Compound 1 effectively lowered the IOP at both dose levels, and its action was more prolonged and pronounced than that of propranolol (Bodor et al., 1988). Administration of 1 to the eye of rabbits was not associated with irritation, contrary to topical administration of propranolol. Propranolol ( 3 ) was detected in the different eye compartments for up to 2 h following administration of the oxime ( 1 ). Propranolol ( 3 ) was not, however, detected in the rat's blood following systemic administration of the oxime." @default.
- W2032020785 created "2016-06-24" @default.
- W2032020785 creator A5000618782 @default.
- W2032020785 creator A5016748557 @default.
- W2032020785 date "1989-08-01" @default.
- W2032020785 modified "2023-10-08" @default.
- W2032020785 title "Formation of propranolol in the iris-ciliary body from its propranolol ketoxime precursor — a potential antiglaucoma drug" @default.
- W2032020785 cites W1809894534 @default.
- W2032020785 cites W1963868900 @default.
- W2032020785 cites W1973148714 @default.
- W2032020785 cites W1980731069 @default.
- W2032020785 cites W2007780884 @default.
- W2032020785 cites W2032038235 @default.
- W2032020785 cites W2047758179 @default.
- W2032020785 cites W2092674260 @default.
- W2032020785 doi "https://doi.org/10.1016/0378-5173(89)90312-8" @default.
- W2032020785 hasPublicationYear "1989" @default.
- W2032020785 type Work @default.
- W2032020785 sameAs 2032020785 @default.
- W2032020785 citedByCount "20" @default.
- W2032020785 countsByYear W20320207852012 @default.
- W2032020785 countsByYear W20320207852016 @default.
- W2032020785 crossrefType "journal-article" @default.
- W2032020785 hasAuthorship W2032020785A5000618782 @default.
- W2032020785 hasAuthorship W2032020785A5016748557 @default.
- W2032020785 hasConcept C118487528 @default.
- W2032020785 hasConcept C126322002 @default.
- W2032020785 hasConcept C184297639 @default.
- W2032020785 hasConcept C185592680 @default.
- W2032020785 hasConcept C2778151854 @default.
- W2032020785 hasConcept C2778434524 @default.
- W2032020785 hasConcept C2779503344 @default.
- W2032020785 hasConcept C2780035454 @default.
- W2032020785 hasConcept C38652104 @default.
- W2032020785 hasConcept C41008148 @default.
- W2032020785 hasConcept C71924100 @default.
- W2032020785 hasConcept C98274493 @default.
- W2032020785 hasConceptScore W2032020785C118487528 @default.
- W2032020785 hasConceptScore W2032020785C126322002 @default.
- W2032020785 hasConceptScore W2032020785C184297639 @default.
- W2032020785 hasConceptScore W2032020785C185592680 @default.
- W2032020785 hasConceptScore W2032020785C2778151854 @default.
- W2032020785 hasConceptScore W2032020785C2778434524 @default.
- W2032020785 hasConceptScore W2032020785C2779503344 @default.
- W2032020785 hasConceptScore W2032020785C2780035454 @default.
- W2032020785 hasConceptScore W2032020785C38652104 @default.
- W2032020785 hasConceptScore W2032020785C41008148 @default.
- W2032020785 hasConceptScore W2032020785C71924100 @default.
- W2032020785 hasConceptScore W2032020785C98274493 @default.
- W2032020785 hasIssue "3" @default.
- W2032020785 hasLocation W20320207851 @default.
- W2032020785 hasOpenAccess W2032020785 @default.
- W2032020785 hasPrimaryLocation W20320207851 @default.
- W2032020785 hasRelatedWork W1964257100 @default.
- W2032020785 hasRelatedWork W2049665104 @default.
- W2032020785 hasRelatedWork W2049854387 @default.
- W2032020785 hasRelatedWork W2093385872 @default.
- W2032020785 hasRelatedWork W2107359378 @default.
- W2032020785 hasRelatedWork W2408765281 @default.
- W2032020785 hasRelatedWork W2412247346 @default.
- W2032020785 hasRelatedWork W2468266982 @default.
- W2032020785 hasRelatedWork W4211240565 @default.
- W2032020785 hasRelatedWork W4313453689 @default.
- W2032020785 hasVolume "53" @default.
- W2032020785 isParatext "false" @default.
- W2032020785 isRetracted "false" @default.
- W2032020785 magId "2032020785" @default.
- W2032020785 workType "article" @default.